Adil Mardinoğlu

Research interests

Publications

• Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation

  Nature Communications · 2023 · 10.1038/s41467-023-41132-w

• A single–cell type transcriptomics map of human tissues

  Science Advances · 2021 · https://doi.org/10.1126/sciadv.abh2169

• Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

  Nature · 2021 · 10.1038/s41586-021-03232-9

• Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease

  Cell Reports · 2021 · 10.1016/j.celrep.2021.108807

• MEMOTE for standardized genome-scale metabolic model testing

  Nature Biotechnology · 2020 · https://doi.org/10.1038/s41587-020-0446-y

• An atlas of the protein-coding genes in the human, pig, and mouse brain

  Science · 2020 · https://doi.org/10.1126/science.aay5947

• An atlas of human metabolism

  Science Signaling · 2020 · https://doi.org/10.1126/scisignal.aaz1482

• A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

  Science · 2019 · https://doi.org/10.1126/science.aax9198

• The human secretome

  Science Signaling · 2019 · https://doi.org/10.1126/scisignal.aaz0274

• Integrative Personal Omics Profiles during Periods of Weight Gain and Loss

  Cell Systems · 2018 · 10.1016/j.cels.2017.12.013

• An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

  Cell Metabolism · 2018 · https://doi.org/10.1016/j.cmet.2018.01.005

• Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes

  Proceedings of the National Academy of Sciences · 2018 · 10.1073/pnas.1807305115

• A pathology atlas of the human cancer transcriptome

  Science · 2017 · 10.1126/science.aan2507

• Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD

  Molecular Systems Biology · 2017 · 10.15252/msb.20167422

• A subcellular map of the human proteome

  Science · 2017 · 10.1126/science.aal3321

• Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance

  Cell Metabolism · 2016 · https://doi.org/10.1016/j.cmet.2016.05.026

• Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

  Cell Metabolism · 2015 · 10.1016/j.cmet.2015.07.001

• The gut microbiota modulates host amino acid and glutathione metabolism in mice

  Molecular Systems Biology · 2015 · https://doi.org/10.15252/msb.20156487

• Tissue-based map of the human proteome

  Science · 2015 · 10.1126/science.1260419

• Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

  Nature Communications · 2014 · https://doi.org/10.1038/ncomms4083

• Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling

  Molecular Systems Biology · 2014 · 10.1002/msb.145122

• Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

  Molecular & Cellular Proteomics · 2013 · 10.1074/mcp.m113.035600

• Understanding the interactions between bacteria in the human gut through metabolic modeling

  Scientific Reports · 2013 · 10.1038/srep02532

• Integration of clinical data with a genome‐scale metabolic model of the human adipocyte

  Molecular Systems Biology · 2013 · 10.1038/msb.2013.5

• Reconstruction of Genome-Scale Active Metabolic Networks for 69 Human Cell Types and 16 Cancer Types Using INIT

  PLoS Computational Biology · 2012 · 10.1371/journal.pcbi.1002518

Current projects

No projects listed.