Sergio Grinstein

Research interests

Publications

• The position of lysosomes within the cell determines their luminal pH

  The Journal of Cell Biology · 2016 · https://doi.org/10.1083/jcb.201507112

• Phagocytosis: receptors, signal integration, and the cytoskeleton

  Immunological Reviews · 2014 · https://doi.org/10.1111/imr.12212

• Scavenger receptors in homeostasis and immunity

  Nature reviews. Immunology · 2013 · https://doi.org/10.1038/nri3515

• The Cell Biology of Phagocytosis

  Annual Review of Pathology Mechanisms of Disease · 2011 · https://doi.org/10.1146/annurev-pathol-011811-132445

• The Distribution and Function of Phosphatidylserine in Cellular Membranes

  Annual Review of Biophysics · 2010 · https://doi.org/10.1146/annurev.biophys.093008.131234

• Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

  The Journal of Cell Biology · 2010 · https://doi.org/10.1083/jcb.200908086

• In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

  Immunity · 2010 · https://doi.org/10.1016/j.immuni.2009.12.006

• Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

  Nature Reviews Microbiology · 2009 · https://doi.org/10.1038/nrmicro2128

• Activation of antibacterial autophagy by NADPH oxidases

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0811045106

• Sensors and regulators of intracellular pH

  Nature Reviews Molecular Cell Biology · 2009 · https://doi.org/10.1038/nrm2820

• Robust single-particle tracking in live-cell time-lapse sequences

  Nature Methods · 2008 · https://doi.org/10.1038/nmeth.1237

• Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

  Science · 2008 · https://doi.org/10.1126/science.1152066

• LAMP proteins are required for fusion of lysosomes with phagosomes

  The EMBO Journal · 2007 · https://doi.org/10.1038/sj.emboj.7601511

• The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

  Nature Immunology · 2006 · https://doi.org/10.1038/ni1297

• The pH of the Secretory Pathway: Measurement, Determinants, and Regulation

  Physiology · 2004 · https://doi.org/10.1152/physiol.00005.2004

• Diversity of the mammalian sodium/proton exchanger SLC9 gene family

  Pflügers Archiv - European Journal of Physiology · 2004 · https://doi.org/10.1007/s00424-003-1110-3

• Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP

  Molecular and Cellular Biology · 2003 · https://doi.org/10.1128/mcb.23.18.6494-6506.2003

• Phagocytosis and innate immunity

  Current Opinion in Immunology · 2002 · https://doi.org/10.1016/s0952-7915(01)00309-0

• Phagosome maturation: aging gracefully

  Biochemical Journal · 2002 · https://doi.org/10.1042/bj20020691

• Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

  The Journal of Cell Biology · 2001 · https://doi.org/10.1083/jcb.200107069

• Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis

  The Journal of Cell Biology · 2000 · https://doi.org/10.1083/jcb.151.7.1353

• The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

  Nature · 1998 · https://doi.org/10.1038/33458

• Na+/H+ Exchangers of Mammalian Cells

  Journal of Biological Chemistry · 1997 · https://doi.org/10.1074/jbc.272.36.22373

• Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

  Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · 1989 · https://doi.org/10.1016/0304-4157(89)90004-x

• Mechanisms of regulation of the Na+/H+ exchanger

  The Journal of Membrane Biology · 1986 · https://doi.org/10.1007/bf01869680

Current projects

No projects listed.