Lars Edvinsson

Research interests

Publications

• Does inflammation have a role in migraine?

  Nature Reviews Neurology · 2019 · https://doi.org/10.1038/s41582-019-0216-y

• CGRP as the target of new migraine therapies — successful translation from bench to clinic

  Nature Reviews Neurology · 2018 · https://doi.org/10.1038/s41582-018-0003-1

• Blocking CGRP in migraine patients – a review of pros and cons

  The Journal of Headache and Pain · 2017 · https://doi.org/10.1186/s10194-017-0807-1

• T he T rigeminovascular P athway: R ole of CGRP and CGRP R eceptors in M igraine

  Headache The Journal of Head and Face Pain · 2017 · https://doi.org/10.1111/head.13081

• CGRP and its receptors provide new insights into migraine pathophysiology

  Nature Reviews Neurology · 2010 · https://doi.org/10.1038/nrneurol.2010.127

• Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion

  Neuroscience · 2010 · https://doi.org/10.1016/j.neuroscience.2010.05.016

• Cerebral Blood Flow and Metabolism

  Headache The Journal of Head and Face Pain · 1994 · https://doi.org/10.1111/j.1526-4610.1994.hed3401059.x

• Human in vivo evidence for trigeminovascular activation in cluster headache Neuropeptide changes and effects of acute attacks therapies

  Brain · 1994 · https://doi.org/10.1093/brain/117.3.427

• The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats

  Annals of Neurology · 1993 · https://doi.org/10.1002/ana.410330109

• Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

  Annals of Neurology · 1990 · https://doi.org/10.1002/ana.410280213

• Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system

  Annals of Neurology · 1988 · https://doi.org/10.1002/ana.410230214

• The concept of coupling blood flow to brain function: Revision required?

  Annals of Neurology · 1987 · https://doi.org/10.1002/ana.410220302

• Calcitonin Gene-Related Peptide and Cerebral Blood Vessels: Distribution and Vasomotor Effects

  Journal of Cerebral Blood Flow & Metabolism · 1987 · https://doi.org/10.1038/jcbfm.1987.126

• Calcitonin gene-related peptide: functional role in cerebrovascular regulation.

  Proceedings of the National Academy of Sciences · 1986 · https://doi.org/10.1073/pnas.83.15.5731

• Calcitonin gene-related peptide (CGRP): perivascular distribution and vasodilatory effects

  Regulatory Peptides · 1986 · https://doi.org/10.1016/0167-0115(86)90071-6

• Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: Trigeminal origin and co-existence with substance P

  Neuroscience Letters · 1985 · https://doi.org/10.1016/0304-3940(85)90296-4

• Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat

  Neuroscience Letters · 1985 · https://doi.org/10.1016/0304-3940(85)90166-1

• Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers

  Regulatory Peptides · 1984 · https://doi.org/10.1016/0167-0115(84)90064-8

• Neuropeptide Y potentiates the effect of various vasoconstrictor agents on rabbit blood vessels

  British Journal of Pharmacology · 1984 · https://doi.org/10.1111/j.1476-5381.1984.tb16516.x

• Neuropeptide Y: Cerebrovascular innervation an vasomotor effects in the cat

  Neuroscience Letters · 1983 · https://doi.org/10.1016/0304-3940(83)90132-5

• Central serotonergic nerves project to the pial vessels of the brain

  Nature · 1983 · https://doi.org/10.1038/306055a0

• Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels*

  Acta Physiologica Scandinavica · 1983 · https://doi.org/10.1111/j.1748-1716.1983.tb07178.x

• Amine mechanisms in the cerebral circulation.

  Pharmacological Reviews · 1976 · https://doi.org/10.1016/s0031-6997(25)06714-6

• Immunohistochemical localization of a vasodilatory polypeptide (VIP) in cerebrovascular nerves

  Brain Research · 1976 · https://doi.org/10.1016/0006-8993(76)90951-3

• Autonomic nerves, mast cells, and amine receptors in human brain vessels. A histochemical and pharmacological study

  Brain Research · 1976 · https://doi.org/10.1016/0006-8993(76)90356-5

Current projects

No projects listed.