Nikolaus Marx

Research interests

Publications

• Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes

  New England Journal of Medicine · 2025 · 10.1056/nejmoa2501006

• 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

  European Heart Journal · 2024 · https://doi.org/10.1093/eurheartj/ehae176

• 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes

  European Heart Journal · 2023 · https://doi.org/10.1093/eurheartj/ehad192

• GLP-1 Receptor Agonists for the Reduction of Atherosclerotic Cardiovascular Risk in Patients With Type 2 Diabetes

  Circulation · 2022 · 10.1161/circulationaha.122.059595

• Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk

  New England Journal of Medicine · 2022 · 10.1056/nejmoa2210645

• Empagliflozin in Heart Failure with a Preserved Ejection Fraction

  New England Journal of Medicine · 2021 · https://doi.org/10.1056/nejmoa2107038

• Swarm Learning for decentralized and confidential clinical machine learning

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03583-3

• Cardiovascular Disease in Chronic Kidney Disease

  Circulation · 2021 · https://doi.org/10.1161/circulationaha.120.050686

• Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting

  Advanced Drug Delivery Reviews · 2020 · 10.1016/j.addr.2020.07.019

• 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

  European Heart Journal · 2019 · https://doi.org/10.1093/eurheartj/ehz486

• Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes

  JAMA · 2019 · 10.1001/jama.2019.13772

• 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

  European Heart Journal · 2019 · https://doi.org/10.1093/eurheartj/ehz486

• Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk

  JAMA · 2018 · 10.1001/jama.2018.18269

• Empagliflozin Increases Cardiac Energy Production in Diabetes

  JACC Basic to Translational Science · 2018 · 10.1016/j.jacbts.2018.07.006

• Type 1 Diabetes Mellitus and Cardiovascular Disease: A Scientific Statement From the American Heart Association and American Diabetes Association

  Diabetes Care · 2014 · 10.2337/dc14-1720

• Type 1 Diabetes Mellitus and Cardiovascular Disease

  Circulation · 2014 · 10.1161/cir.0000000000000034

• T-lymphocyte Infiltration in Visceral Adipose Tissue

  Arteriosclerosis Thrombosis and Vascular Biology · 2008 · 10.1161/atvbaha.108.165100

• The Residual Risk Reduction Initiative: A Call to Action to Reduce Residual Vascular Risk in Patients with Dyslipidemia

  The American Journal of Cardiology · 2008 · 10.1016/j.amjcard.2008.10.002

• PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

  Cell Metabolism · 2007 · 10.1016/j.cmet.2007.06.010

• Peroxisome Proliferator-Activated Receptors and Atherogenesis

  Circulation Research · 2004 · 10.1161/01.res.0000127122.22685.0a

• PPARγ Activation in Human Endothelial Cells Increases Plasminogen Activator Inhibitor Type-1 Expression

  Arteriosclerosis Thrombosis and Vascular Biology · 1999 · 10.1161/01.atv.19.3.546

• PPARα Activators Inhibit Cytokine-Induced Vascular Cell Adhesion Molecule-1 Expression in Human Endothelial Cells

  Circulation · 1999 · 10.1161/01.cir.99.24.3125

• Macrophages in Human Atheroma Contain PPARγ

  American Journal Of Pathology · 1998 · 10.1016/s0002-9440(10)65540-x

• Peroxisome Proliferator-Activated Receptor Gamma Activators Inhibit Gene Expression and Migration in Human Vascular Smooth Muscle Cells

  Circulation Research · 1998 · 10.1161/01.res.83.11.1097

• Induction of Cytokine Expression in Leukocytes by Binding of Thrombin-Stimulated Platelets

  Circulation · 1997 · 10.1161/01.cir.95.10.2387

Current projects

No projects listed.