Christian Drosten

Research interests

Publications

• Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

  Science · 2020 · 10.1126/science.abb7314

• Virological assessment of hospitalized patients with COVID-2019

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2196-x

• Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

  Nature Neuroscience · 2020 · 10.1038/s41593-020-00758-5

• SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

  Nature · 2020 · 10.1038/s41586-020-2598-9

• COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

  Nature Biotechnology · 2020 · 10.1038/s41587-020-0602-4

• Severe Acute Respiratory Syndrome Coronavirus 2−Specific Antibody Responses in Coronavirus Disease Patients

  Emerging infectious diseases · 2020 · https://doi.org/10.3201/eid2607.200841

• The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

  bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 10.1101/2020.01.31.929042

• Severe acute respiratory syndrome-related coronavirus : The species and its viruses – a statement of the Coronavirus Study Group

  bioRxiv (Cold Spring Harbor Laboratory) · 2020 · https://doi.org/10.1101/2020.02.07.937862

• Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.08.001

• SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

  Cell · 2020 · 10.1016/j.cell.2020.02.052

• Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

  Eurosurveillance · 2020 · 10.2807/1560-7917.es.2020.25.3.2000045

• The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

  Nature Microbiology · 2020 · 10.1038/s41564-020-0695-z

• The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

  International Journal of Infectious Diseases · 2020 · https://doi.org/10.1016/j.ijid.2020.01.009

• Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany

  New England Journal of Medicine · 2020 · 10.1056/nejmc2001468

• Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

  Science · 2020 · 10.1126/science.abb3405

• Hosts and Sources of Endemic Human Coronaviruses

  Advances in virus research · 2018 · 10.1016/bs.aivir.2018.01.001

• Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

  The Lancet Infectious Diseases · 2013 · 10.1016/s1473-3099(13)70164-6

• Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

  Nature · 2013 · 10.1038/nature12005

• Commentary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

  Journal of Virology · 2013 · 10.1128/jvi.01244-13

• Bats host major mammalian paramyxoviruses

  Nature Communications · 2012 · 10.1038/ncomms1796

• Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

  Journal of Virology · 2011 · 10.1128/jvi.02232-10

• Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

  Science · 2003 · 10.1126/science.1085952

• Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

  New England Journal of Medicine · 2003 · 10.1056/nejmoa030747

• Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome

  The Lancet · 2003 · 10.1016/s0140-6736(03)13967-0

• Rapid Detection and Quantification of RNA of Ebola and Marburg Viruses, Lassa Virus, Crimean-Congo Hemorrhagic Fever Virus, Rift Valley Fever Virus, Dengue Virus, and Yellow Fever Virus by Real-Time Reverse Transcription-PCR

  Journal of Clinical Microbiology · 2002 · 10.1128/jcm.40.7.2323-2330.2002

Current projects

No projects listed.