Hiroshi Sakagami

Research interests

Publications

• ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?

  Viruses · 2020 · 10.3390/v12050491

• Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

  Bioorganic Chemistry · 2018 · 10.1016/j.bioorg.2018.12.028

• New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors

  Bioorganic Chemistry · 2018 · 10.1016/j.bioorg.2018.01.021

• Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

  Bioorganic Chemistry · 2018 · 10.1016/j.bioorg.2018.12.028

• Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

  Bioorganic Chemistry · 2018 · 10.1016/j.bioorg.2018.12.028

• Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

  Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 · 10.3109/14756366.2016.1160077

• Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

  Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 · 10.3109/14756366.2016.1160077

• Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides

  Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 · 10.3109/14756366.2016.1160077

• Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass ionomer cement

  Journal of Applied Oral Science · 2015 · 10.1590/1678-775720140496

• Distribution of lignin–carbohydrate complex in plant kingdom and its functionality as alternative medicine

  Pharmacology & Therapeutics · 2010 · 10.1016/j.pharmthera.2010.05.004

• Distribution of lignin–carbohydrate complex in plant kingdom and its functionality as alternative medicine

  Pharmacology & Therapeutics · 2010 · 10.1016/j.pharmthera.2010.05.004

• Distribution of lignin–carbohydrate complex in plant kingdom and its functionality as alternative medicine

  Pharmacology & Therapeutics · 2010 · 10.1016/j.pharmthera.2010.05.004

• Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids.

  PubMed · 2005

• Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids.

  PubMed · 2005

• Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids.

  PubMed · 2005

• Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).

  PubMed · 2004

• Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).

  PubMed · 2004

• Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).

  PubMed · 2004

• Radical scavenging activity and cytotoxicity of ferulic acid.

  PubMed · 2003

• Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra

  Fitoterapia · 2003 · 10.1016/s0367-326x(03)00164-3

• Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra

  Fitoterapia · 2003 · 10.1016/s0367-326x(03)00164-3

• Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra

  Fitoterapia · 2003 · 10.1016/s0367-326x(03)00164-3

• Biological activity of persimmon (Diospyros kaki) peel extracts

  Phytotherapy Research · 2003 · 10.1002/ptr.1183

• Biological activity of persimmon (Diospyros kaki) peel extracts

  Phytotherapy Research · 2003 · 10.1002/ptr.1183

• Biological activity of persimmon (Diospyros kaki) peel extracts

  Phytotherapy Research · 2003 · 10.1002/ptr.1183

• Radical scavenging activity and cytotoxicity of ferulic acid.

  PubMed · 2003

• Radical scavenging activity and cytotoxicity of ferulic acid.

  PubMed · 2003

• Production of bioactive triterpenes by Eriobotrya japonica calli

  Phytochemistry · 2002 · 10.1016/s0031-9422(01)00455-1

• Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts

  Journal of Ethnopharmacology · 2002 · 10.1016/s0378-8741(02)00125-3

• 3,5-Dibenzoyl-1,4-dihydropyridines: Synthesis and MDR Reversal in Tumor Cells

  Bioorganic & Medicinal Chemistry · 2002 · 10.1016/s0968-0896(01)00363-7

• Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts

  Journal of Ethnopharmacology · 2002 · 10.1016/s0378-8741(02)00125-3

• Antioxidant and prooxidant action of eugenol-related compounds and their cytotoxicity

  Toxicology · 2002 · 10.1016/s0300-483x(02)00194-4

• Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts

  Journal of Ethnopharmacology · 2002 · 10.1016/s0378-8741(02)00125-3

• Cytotoxic Flavonoids with Isoprenoid Groups from Morus mongolica

  Journal of Natural Products · 2001 · 10.1021/np000317c

• Apoptosis-inducing activity of vitamin C and vitamin K.

  PubMed · 2000

• Cytotoxic activity of hydrolyzable tannins against human oral tumor cell lines — A possible mechanism

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80020-3

• Antitumor Potential and Possible Targets of Phenothiazine-Related Compounds

  Current Drug Targets · 2000 · 10.2174/1389450003349191

• Antitumor Potential and Possible Targets of Phenothiazine-Related Compounds

  Current Drug Targets · 2000 · 10.2174/1389450003349191

• Cytotoxic activity of hydrolyzable tannins against human oral tumor cell lines — A possible mechanism

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80020-3

• The ERK-1/2 Signaling Pathway Is Involved in the Stimulation of Branching Morphogenesis of Fetal Mouse Submandibular Glands by EGF

  Developmental Biology · 2000 · 10.1006/dbio.2000.9639

• Induction of cytotoxicity by chlorogenic acid in human oral tumor cell lines

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80034-3

• Apoptosis-inducing activity of vitamin C and vitamin K.

  PubMed · 2000

• Apoptosis-inducing activity of vitamin C and vitamin K.

  PubMed · 2000

• Polyphenols from Eriobotrya japonica and Their Cytotoxicity against Human Oral Tumor Cell Lines.

  Chemical and Pharmaceutical Bulletin · 2000 · 10.1248/cpb.48.687

• The ERK-1/2 Signaling Pathway Is Involved in the Stimulation of Branching Morphogenesis of Fetal Mouse Submandibular Glands by EGF

  Developmental Biology · 2000 · 10.1006/dbio.2000.9639

• Induction of cytotoxicity by chlorogenic acid in human oral tumor cell lines

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80034-3

• The ERK-1/2 Signaling Pathway Is Involved in the Stimulation of Branching Morphogenesis of Fetal Mouse Submandibular Glands by EGF

  Developmental Biology · 2000 · 10.1006/dbio.2000.9639

• Induction of cytotoxicity by chlorogenic acid in human oral tumor cell lines

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80034-3

• Cytotoxic activity of hydrolyzable tannins against human oral tumor cell lines — A possible mechanism

  Phytomedicine · 2000 · 10.1016/s0944-7113(00)80020-3

• Antitumor Potential and Possible Targets of Phenothiazine-Related Compounds

  Current Drug Targets · 2000 · 10.2174/1389450003349191

• Inhibition of human immunodeficiency viral replication by tannins and related compounds

  Antiviral Research · 1992 · 10.1016/0166-3542(92)90008-s

• Inhibition of herpes simplex virus infection by tannins and related compounds

  Antiviral Research · 1989 · 10.1016/0166-3542(89)90038-7

• Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

  Proceedings of the National Academy of Sciences · 1981 · https://doi.org/10.1073/pnas.78.8.4990

Current projects

No projects listed.