Bernhard Hube

Research interests

Publications

• Immune regulation by fungal strain diversity in inflammatory bowel disease

  Nature · 2022 · 10.1038/s41586-022-04502-w

• The impact of the Fungus-Host-Microbiota interplay uponCandida albicansinfections: current knowledge and new perspectives

  FEMS Microbiology Reviews · 2020 · 10.1093/femsre/fuaa060

• Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.01.041

• The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

  Nature Communications · 2018 · 10.1038/s41467-018-06607-1

• Fungi that Infect Humans

  Microbiology Spectrum · 2017 · 10.1128/microbiolspec.funk-0014-2016

• Candidalysin is a fungal peptide toxin critical for mucosal infection

  Nature · 2016 · https://doi.org/10.1038/nature17625

• Candida albicans pathogenicity mechanisms

  Virulence · 2013 · https://doi.org/10.4161/viru.22913

• Importance of the Candida albicans cell wall during commensalism and infection

  Current Opinion in Microbiology · 2012 · 10.1016/j.mib.2012.04.005

• Candida albicans interactions with epithelial cells and mucosal immunity

  Microbes and Infection · 2011 · 10.1016/j.micinf.2011.06.009

• Candida albicans dimorphism as a therapeutic target

  Expert Review of Anti-infective Therapy · 2011 · 10.1586/eri.11.152

• From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells

  PLoS ONE · 2011 · 10.1371/journal.pone.0017046

• Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes

  Cellular Microbiology · 2009 · 10.1111/j.1462-5822.2009.01394.x

• Evolution of pathogenicity and sexual reproduction in eight Candida genomes

  Nature · 2009 · https://doi.org/10.1038/nature08064

• The Hyphal-Associated Adhesin and Invasin Als3 of Candida albicans Mediates Iron Acquisition from Host Ferritin

  PLoS Pathogens · 2008 · 10.1371/journal.ppat.1000217

• In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination

  Cellular Microbiology · 2007 · 10.1111/j.1462-5822.2007.01009.x

• Glycosylphosphatidylinositol-anchored Proteases of Candida albicans Target Proteins Necessary for Both Cellular Processes and Host-Pathogen Interactions

  Journal of Biological Chemistry · 2005 · 10.1074/jbc.m509297200

• Hydrolytic enzymes as virulence factors of Candida albicans

  Mycoses · 2005 · 10.1111/j.1439-0507.2005.01165.x

• Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood

  Molecular Microbiology · 2005 · 10.1111/j.1365-2958.2005.04557.x

• Candida albicans proteinases and host/pathogen interactions

  Cellular Microbiology · 2004 · 10.1111/j.1462-5822.2004.00439.x

• Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

  Microbiology and Molecular Biology Reviews · 2003 · https://doi.org/10.1128/mmbr.67.3.400-428.2003

• Candida albicans Hyphal Formation and the Expression of the Efg1-Regulated Proteinases Sap4 to Sap6 Are Required for the Invasion of Parenchymal Organs

  Infection and Immunity · 2002 · 10.1128/iai.70.7.3689-3700.2002

• Candida albicans proteinases: resolving the mystery of a gene family

  Microbiology · 2001 · 10.1099/00221287-147-8-1997

• A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence

  Infection and Immunity · 1997 · 10.1128/iai.65.9.3539-3546.1997

• Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence

  Infection and Immunity · 1997 · 10.1128/iai.65.9.3529-3538.1997

• Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans

  Molecular Microbiology · 1994 · 10.1111/j.1365-2958.1994.tb01269.x

Current projects

No projects listed.