Michael J. Mitchell

Research interests

Publications

• Nanoparticle protein corona: from structure and function to therapeutic targeting

  Lab on a Chip · 2023 · https://doi.org/10.1039/d2lc00799a

• Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

  Nature Nanotechnology · 2023 · https://doi.org/10.1038/s41565-023-01404-4

• In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism

  Small · 2023 · https://doi.org/10.1002/smll.202304378

• Ionizable lipid nanoparticles for in utero mRNA delivery

  Science Advances · 2021 · https://doi.org/10.1126/sciadv.aba1028

• Microfluidic formulation of nanoparticles for biomedical applications

  Biomaterials · 2021 · https://doi.org/10.1016/j.biomaterials.2021.120826

• An ionizable lipid toolbox for RNA delivery

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-27493-0

• Nanomaterials for T-cell cancer immunotherapy

  Nature Nanotechnology · 2021 · https://doi.org/10.1038/s41565-020-00822-y

• Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device

  Nano Letters · 2021 · https://doi.org/10.1021/acs.nanolett.1c01353

• Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering

  Nano Letters · 2020 · https://doi.org/10.1021/acs.nanolett.9b04246

• Engineering precision nanoparticles for drug delivery

  Nature Reviews Drug Discovery · 2020 · https://doi.org/10.1038/s41573-020-0090-8

• Proton-driven transformable nanovaccine for cancer immunotherapy

  Nature Nanotechnology · 2020 · https://doi.org/10.1038/s41565-020-00782-3

• Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver

  Biomaterials Science · 2020 · https://doi.org/10.1039/d0bm01609h

• Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening

  Journal of Controlled Release · 2019 · https://doi.org/10.1016/j.jconrel.2019.10.028

• Delivery technologies for cancer immunotherapy

  Nature Reviews Drug Discovery · 2019 · https://doi.org/10.1038/s41573-018-0006-z

• Advances in Biomaterials for Drug Delivery

  Advanced Materials · 2018 · https://doi.org/10.1002/adma.201705328

• Engineering and physical sciences in oncology: challenges and opportunities

  Nature reviews. Cancer · 2017 · https://doi.org/10.1038/nrc.2017.83

• Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

  Nano Letters · 2016 · https://doi.org/10.1021/acs.nanolett.6b03329

• Computational and Experimental Models of Cancer Cell Response to Fluid Shear Stress

  Frontiers in Oncology · 2013 · https://doi.org/10.3389/fonc.2013.00044

Current projects

No projects listed.