Hiromitsu Nakauchi

Research interests

Publications

• ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

  Stem Cell Reports · 2021 · https://doi.org/10.1016/j.stemcr.2021.05.012

• Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1244-x

• Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche

  Nature · 2016 · https://doi.org/10.1038/nature16943

• Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation

  Cell stem cell · 2015 · https://doi.org/10.1016/j.stem.2015.03.004

• Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation

  Cell stem cell · 2013 · https://doi.org/10.1016/j.stem.2012.11.002

• Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.08.007

• A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

  Cell · 2012 · https://doi.org/10.1016/j.cell.2012.01.040

• Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

  Cell · 2011 · https://doi.org/10.1016/j.cell.2011.09.053

• Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

  Cell stem cell · 2011 · https://doi.org/10.1016/j.stem.2010.11.029

• Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

  Cell · 2010 · https://doi.org/10.1016/j.cell.2010.07.039

• Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

  The Journal of Experimental Medicine · 2010 · https://doi.org/10.1084/jem.20100844

• Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

  The Journal of Experimental Medicine · 2010 · https://doi.org/10.1084/jem.20091318

• Development of Defective and Persistent Sendai Virus Vector

  Journal of Biological Chemistry · 2010 · https://doi.org/10.1074/jbc.m110.183780

• Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1937

• Side population purified from hepatocellular carcinoma cells harbors cancer stem cell–like properties

  Hepatology · 2006 · https://doi.org/10.1002/hep.21227

• The Transcriptional Landscape of the Mammalian Genome

  Science · 2005 · https://doi.org/10.1126/science.1112014

• Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product Bmi-1

  Immunity · 2004 · https://doi.org/10.1016/j.immuni.2004.11.004

• Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver

  The Journal of Cell Biology · 2002 · https://doi.org/10.1083/jcb.200108066

• The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

  Nature Medicine · 2001 · https://doi.org/10.1038/nm0901-1028

• Fcα/μ receptor mediates endocytosis of IgM-coated microbes

  Nature Immunology · 2000 · https://doi.org/10.1038/80886

• Age-Associated Characteristics of Murine Hematopoietic Stem Cells

  The Journal of Experimental Medicine · 2000 · https://doi.org/10.1084/jem.192.9.1273

• Expansion of hematopoietic stem cells in the developing liver of a mouse embryo

  Blood · 2000 · https://doi.org/10.1182/blood.v95.7.2284

• Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

  Science · 1996 · https://doi.org/10.1126/science.273.5272.242

• Developmental defects of lymphoid cells in Jak3 kinase-deficient mice

  Immunity · 1995 · https://doi.org/10.1016/1074-7613(95)90066-7

• In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells

  Blood · 1992 · https://doi.org/10.1182/blood.v80.12.3044.3044

• Expression and function of c-kit in hemopoietic progenitor cells.

  The Journal of Experimental Medicine · 1991 · https://doi.org/10.1084/jem.174.1.63

Current projects

No projects listed.