Ash A. Alizadeh

Research interests

Publications

• From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment

  Cell · 2023 · 10.1016/j.cell.2023.01.035

• Profiling Cell Type Abundance and Expression in Bulk Tissues with CIBERSORTx

  Methods in molecular biology · 2020 · 10.1007/978-1-0716-0301-7_7

• Outcomes of Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer

  JAMA Oncology · 2020 · https://doi.org/10.1001/jamaoncol.2020.0147

• Integrating genomic features for non-invasive early lung cancer detection

  Nature · 2020 · 10.1038/s41586-020-2140-0

• Determining cell type abundance and expression from bulk tissues with digital cytometry

  Nature Biotechnology · 2019 · https://doi.org/10.1038/s41587-019-0114-2

• Profiling Tumor Infiltrating Immune Cells with CIBERSORT

  Methods in molecular biology · 2018 · https://doi.org/10.1007/978-1-4939-7493-1_12

• Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-17-0716

• Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients

  Nature Communications · 2016 · 10.1038/ncomms11815

• Integrated digital error suppression for improved detection of circulating tumor DNA

  Nature Biotechnology · 2016 · 10.1038/nbt.3520

• The prognostic landscape of genes and infiltrating immune cells across human cancers

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3909

• Robust enumeration of cell subsets from tissue expression profiles

  Nature Methods · 2015 · 10.1038/nmeth.3337

• Toward understanding and exploiting tumor heterogeneity

  Nature Medicine · 2015 · 10.1038/nm.3915

• An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

  Nature Medicine · 2014 · 10.1038/nm.3519

• The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

  Proceedings of the National Academy of Sciences · 2012 · 10.1073/pnas.1121623109

• Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

  Cell · 2010 · 10.1016/j.cell.2010.07.044

• Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

  Science Translational Medicine · 2010 · 10.1126/scitranslmed.3001375

• CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

  Cell · 2009 · 10.1016/j.cell.2009.05.045

• Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

  PLoS Biology · 2004 · 10.1371/journal.pbio.0020007

• Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes

  New England Journal of Medicine · 2004 · 10.1056/nejmoa032520

• Individuality and variation in gene expression patterns in human blood

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.252784499

• Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

  The Journal of Experimental Medicine · 2001 · 10.1084/jem.194.11.1639

• 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns

  Genome biology · 2000 · 10.1186/gb-2000-1-2-research0003

• Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

  Nature · 2000 · 10.1038/35000501

• Genome-wide analysis of DNA copy number variation in breast cancer using DNA microarrays

  Nature Genetics · 1999 · 10.1038/14385

• Genome-wide analysis of DNA copy-number changes using cDNA microarrays

  Nature Genetics · 1999 · 10.1038/12640

Current projects

No projects listed.