Robert A. Weinberg

Research interests

Publications

• Guidelines and definitions for research on epithelial–mesenchymal transition

  Nature Reviews Molecular Cell Biology · 2020 · https://doi.org/10.1038/s41580-020-0237-9

• Understanding the tumor immune microenvironment (TIME) for effective therapy

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0014-x

• New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

  Nature Reviews Molecular Cell Biology · 2018 · 10.1038/s41580-018-0080-4

• Emerging Biological Principles of Metastasis

  Cell · 2017 · 10.1016/j.cell.2016.11.037

• EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

  Nature Reviews Clinical Oncology · 2017 · 10.1038/nrclinonc.2017.44

• Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

  Cell · 2012 · https://doi.org/10.1016/j.cell.2012.02.008

• Tumor Metastasis: Molecular Insights and Evolving Paradigms

  Cell · 2011 · 10.1016/j.cell.2011.09.024

• A Perspective on Cancer Cell Metastasis

  Science · 2011 · 10.1126/science.1203543

• Hallmarks of Cancer: The Next Generation

  Cell · 2011 · https://doi.org/10.1016/j.cell.2011.02.013

• miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

  Nature Cell Biology · 2010 · https://doi.org/10.1038/ncb2024

• Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

  Cell · 2009 · 10.1016/j.cell.2009.06.034

• The basics of epithelial-mesenchymal transition

  Journal of Clinical Investigation · 2009 · https://doi.org/10.1172/jci39104

• Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

  Nature reviews. Cancer · 2009 · 10.1038/nrc2620

• An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

  Nature Genetics · 2008 · 10.1038/ng.127

• The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

  Cell · 2008 · https://doi.org/10.1016/j.cell.2008.03.027

• Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

  Developmental Cell · 2008 · 10.1016/j.devcel.2008.05.009

• Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

  Nature · 2007 · 10.1038/nature06174

• Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

  Nature · 2007 · 10.1038/nature06188

• Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

  Cell · 2005 · 10.1016/j.cell.2005.02.034

• Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

  Cell · 2004 · 10.1016/j.cell.2004.06.006

• Reconstruction of functionally normal and malignant human breast tissues in mice

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0401064101

• Lentivirus-delivered stable gene silencing by RNAi in primary cells

  RNA · 2003 · 10.1261/rna.2192803

• hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

  Cell · 2001 · 10.1016/s0092-8674(01)00527-x

• The Hallmarks of Cancer

  Cell · 2000 · https://doi.org/10.1016/s0092-8674(00)81683-9

• Creation of human tumour cells with defined genetic elements

  Nature · 1999 · 10.1038/22780

• hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

  Cell · 1997 · 10.1016/s0092-8674(00)80538-3

• Cyclin D1 provides a link between development and oncogenesis in the retina and breast

  Cell · 1995 · 10.1016/0092-8674(95)90034-9

• The retinoblastoma protein and cell cycle control

  Cell · 1995 · 10.1016/0092-8674(95)90385-2

• Tumor spectrum analysis in p53-mutant mice

  Current Biology · 1994 · 10.1016/s0960-9822(00)00002-6

• Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185

  Cell · 1986 · 10.1016/0092-8674(86)90779-8

• The neu oncogene encodes an epidermal growth factor receptor-related protein

  Nature · 1986 · 10.1038/319226a0

• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  Nature · 1986 · 10.1038/323643a0

• Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

  Nature · 1983 · 10.1038/304596a0

Current projects

No projects listed.