Yuval Dor

Research interests

Publications

• A DNA methylation atlas of normal human cell types

  Nature · 2023 · 10.1038/s41586-022-05580-6

• Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

  Cell Reports · 2019 · 10.1016/j.celrep.2019.05.095

• Principles of DNA methylation and their implications for biology and medicine

  The Lancet · 2018 · 10.1016/s0140-6736(18)31268-6

• Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

  Nature Communications · 2018 · 10.1038/s41467-018-03961-y

• Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-07466-6

• Identification of tissue-specific cell death using methylation patterns of circulating DNA

  Proceedings of the National Academy of Sciences · 2016 · 10.1073/pnas.1519286113

• CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq

  Genome biology · 2016 · https://doi.org/10.1186/s13059-016-0938-8

• p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

  Nature Medicine · 2016 · 10.1038/nm.4054

• Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

  Cell · 2012 · 10.1016/j.cell.2012.10.053

• miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors

  The EMBO Journal · 2011 · 10.1038/emboj.2010.361

• Control of Pancreatic β Cell Regeneration by Glucose Metabolism

  Cell Metabolism · 2011 · 10.1016/j.cmet.2011.02.012

• The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

  Cell · 2010 · 10.1016/j.cell.2009.12.041

• Recovery from diabetes in mice by β cell regeneration

  Journal of Clinical Investigation · 2007 · 10.1172/jci32959

• In Vivo Lineage Tracing Defines the Role of Acinar-to-Ductal Transdifferentiation in Inflammatory Ductal Metaplasia

  Gastroenterology · 2007 · 10.1053/j.gastro.2007.09.009

• VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells

  Cell · 2006 · https://doi.org/10.1016/j.cell.2005.10.036

• Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

  Genes & Development · 2005 · 10.1101/gad.351605

• β-Catenin is essential for pancreatic acinar but not islet development

  Development · 2005 · 10.1242/dev.02063

• Pten constrains centroacinar cell expansion and malignant transformation in the pancreas

  Cancer Cell · 2005 · 10.1016/j.ccr.2005.07.015

• Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

  Nature · 2004 · https://doi.org/10.1038/nature02520

• Conditional switching of VEGF provides new insights into adult neovascularization and pro‐angiogenic therapy

  The EMBO Journal · 2002 · 10.1093/emboj/21.8.1939

• Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

  Nature Medicine · 2002 · 10.1038/nm721

• Erratum: Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

  Nature Medicine · 2002 · 10.1038/nm1102-1329b

• A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects

  Development · 2001 · 10.1242/dev.128.9.1531

• Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis

  American Journal of Physiology-Cell Physiology · 2001 · 10.1152/ajpcell.2001.280.6.c1367

• Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

  Nature · 1998 · https://doi.org/10.1038/28867

Current projects

No projects listed.