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Stephen S. Leonard

Researcher Next ID · RN-027104

Researcher · Environmental Science

National Institute for Occupational Safety and Health

Washington D.C., Kenya

Not currently recruitingFunding unknown
Works count
178
Citation count
12,449
H-index
59
i10-index
134

Research interests

Environmental Science
Materials Science
Medicine
Air Quality and Health Impacts
Nanoparticles: synthesis and applications
Occupational and environmental lung diseases
Chromium effects and bioremediation
Heavy Metal Exposure and Toxicity

Publications

  • Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes

    Nanotoxicology · 2012 · 10.3109/17435390.2012.719649

  • Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?

    Toxicology and Applied Pharmacology · 2011 · 10.1016/j.taap.2011.02.001

  • Concept of Assessing Nanoparticle Hazards Considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics

    Journal of Toxicology and Environmental Health · 2010 · 10.1080/15287390903489422

  • Shape-Enhanced Photocatalytic Activity of Single-Crystalline Anatase TiO2 (101) Nanobelts

    Journal of the American Chemical Society · 2010 · https://doi.org/10.1021/ja909456f

  • Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

    Toxicology · 2009 · https://doi.org/10.1016/j.tox.2009.10.017

  • Diabetic cardiomyopathy-associated dysfunction in spatially distinct mitochondrial subpopulations

    American Journal of Physiology-Heart and Circulatory Physiology · 2008 · 10.1152/ajpheart.00467.2008

  • Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes

    Toxicology · 2008 · 10.1016/j.tox.2008.12.023

  • Luteolin and Chrysin Differentially Inhibit Cyclooxygenase-2 Expression and Scavenge Reactive Oxygen Species but Similarly Inhibit Prostaglandin-E2 Formation in RAW 264.7 Cells

    Journal of Nutrition · 2006 · 10.1093/jn/136.6.1517

  • Cardiovascular Effects of Pulmonary Exposure to Single-Wall Carbon Nanotubes

    Environmental Health Perspectives · 2006 · 10.1289/ehp.9688

  • S-Nitrosylation of Bcl-2 Inhibits Its Ubiquitin-Proteasomal Degradation

    Journal of Biological Chemistry · 2006 · 10.1074/jbc.m602551200

  • Cadmium inhibits the electron transfer chain and induces Reactive Oxygen Species

    Free Radical Biology and Medicine · 2004 · https://doi.org/10.1016/j.freeradbiomed.2004.03.010

  • Metal-induced oxidative stress and signal transduction

    Free Radical Biology and Medicine · 2004 · https://doi.org/10.1016/j.freeradbiomed.2004.09.010

  • Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses

    Biochemical and Biophysical Research Communications · 2003 · https://doi.org/10.1016/j.bbrc.2003.08.105

  • Arsenite induces HIF-1α and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells

    Molecular and Cellular Biochemistry · 2003 · 10.1023/b:mcbi.0000007259.65742.16

  • Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest

    Free Radical Biology and Medicine · 2003 · 10.1016/s0891-5849(03)00145-x

  • Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses

    Molecular and Cellular Biochemistry · 2003 · 10.1023/b:mcbi.0000007255.72746.a6

  • Vanadate-induced Expression of Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor through Phosphatidylinositol 3-Kinase/Akt Pathway and Reactive Oxygen Species

    Journal of Biological Chemistry · 2002 · 10.1074/jbc.m200082200

  • p38 Signaling-mediated Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor Induction by Cr(VI) in DU145 Human Prostate Carcinoma Cells

    Journal of Biological Chemistry · 2002 · 10.1074/jbc.m202775200

  • Interleukin-10-mediated inhibition of free radical generation in macrophages

    American Journal of Physiology-Lung Cellular and Molecular Physiology · 2001 · 10.1152/ajplung.2001.280.6.l1196

  • Vanadate-Induced Cell Growth Regulation and the Role of Reactive Oxygen Species

    Archives of Biochemistry and Biophysics · 2001 · 10.1006/abbi.2001.2464

  • Vanadate Induces p53 Transactivation through Hydrogen Peroxide and Causes Apoptosis

    Journal of Biological Chemistry · 2000 · 10.1074/jbc.m005366200

  • Antioxidant properties of aspirin: Characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-κB activation, and TNF-α production

    Molecular and Cellular Biochemistry · 1999 · 10.1023/a:1006934612368

  • Role of Reactive Oxygen Species and p53 in Chromium(VI)-induced Apoptosis

    Journal of Biological Chemistry · 1999 · 10.1074/jbc.274.49.34974

  • Cobalt-mediated generation of reactive oxygen species and its possible mechanism

    Journal of Inorganic Biochemistry · 1998 · 10.1016/s0162-0134(98)10022-3

  • Freshly Fractured Quartz Inhalation Leads to Enhanced Lung Injury and Inflammation. Potential Role of Free Radicals

    American Journal of Respiratory and Critical Care Medicine · 1995 · 10.1164/ajrccm.152.3.7663775

Current projects

    No projects listed.