Lin Leng
Researcher Next ID · RN-027132
Researcher · Immunology and Microbiology
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Bangladesh
- Works count
- 289
- Citation count
- 17,010
- H-index
- 70
- i10-index
- 195
Research interests
Publications
The D -dopachrome tautomerase ( DDT ) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)
Proceedings of the National Academy of Sciences · 2011 · 10.1073/pnas.1102941108
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1002716107
Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D
The Journal of Immunology · 2008 · 10.4049/jimmunol.180.11.7338
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
Nature · 2008 · 10.1038/nature06504
Macrophage Migration Inhibitory Factor Induces B Cell Survival by Activation of a CD74-CD44 Receptor Complex
Journal of Biological Chemistry · 2007 · 10.1074/jbc.m703265200
Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity
Oncogene · 2007 · 10.1038/sj.onc.1210318
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
Nature Medicine · 2007 · https://doi.org/10.1038/nm1567
IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival
Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0701553104
CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex
Immunity · 2006 · 10.1016/j.immuni.2006.08.020
Inhibition of Macrophage Migration Inhibitory Factor or Its Receptor (CD74) Attenuates Growth and Invasion of DU-145 Prostate Cancer Cells
The Journal of Immunology · 2006 · 10.4049/jimmunol.177.12.8730
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity
Cellular Signalling · 2005 · 10.1016/j.cellsig.2005.06.013
Role for macrophage migration inhibitory factor in asthma
Proceedings of the National Academy of Sciences · 2005 · 10.1073/pnas.0507189102
Macrophage migration inhibitory factor
Critical Care Medicine · 2005 · 10.1097/01.ccm.0000191278.04636.d8
MIF Signal Transduction Initiated by Binding to CD74
The Journal of Experimental Medicine · 2003 · https://doi.org/10.1084/jem.20030286
High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers.
PubMed · 2002
Current projects
No projects listed.