David W. C. MacMillan

Research interests

Publications

• Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysis

  Chemical Reviews · 2021 · 10.1021/acs.chemrev.1c00383

• The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future

  Organic Process Research & Development · 2019 · 10.1021/acs.oprd.9b00140

• Visible Light Photocatalysis in Organic Chemistry

  · 2018 · 10.1002/9783527674145

• The merger of transition metal and photocatalysis

  Nature Reviews Chemistry · 2017 · https://doi.org/10.1038/s41570-017-0052

• Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

  Science · 2017 · https://doi.org/10.1126/science.aap9674

• Photoredox Catalysis in Organic Chemistry

  The Journal of Organic Chemistry · 2016 · https://doi.org/10.1021/acs.joc.6b01449

• Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

  Science · 2016 · https://doi.org/10.1126/science.aag0209

• Native functionality in triple catalytic cross-coupling: sp 3 C–H bonds as latent nucleophiles

  Science · 2016 · 10.1126/science.aaf6635

• O–H hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols

  Science · 2015 · 10.1126/science.aac8555

• Alcohols as alkylating agents in heteroarene C–H functionalization

  Nature · 2015 · 10.1038/nature14885

• Switching on elusive organometallic mechanisms with photoredox catalysis

  Nature · 2015 · 10.1038/nature14875

• Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp 3 -carbons with aryl halides

  Science · 2014 · 10.1126/science.1255525

• Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

  Chemical Reviews · 2013 · https://doi.org/10.1021/cr300503r

• Synergistic catalysis: A powerful synthetic strategy for new reaction development

  Chemical Science · 2012 · 10.1039/c2sc00907b

• Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

  Nature · 2011 · 10.1038/nature10647

• Discovery of an α-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity

  Science · 2011 · 10.1126/science.1213920

• Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

  Journal of the American Chemical Society · 2009 · 10.1021/ja9053338

• Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

  Science · 2008 · 10.1126/science.1161976

• The advent and development of organocatalysis

  Nature · 2008 · 10.1038/nature07367

• Modern strategies in organic catalysis: The advent and development of iminium activation

  Aldrichimica acta · 2006

• Enantioselective Organocatalytic Reductive Amination

  Journal of the American Chemical Society · 2005 · 10.1021/ja057222n

• Enantioselective Organo-Cascade Catalysis

  Journal of the American Chemical Society · 2005 · 10.1021/ja055545d

• The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes

  Journal of the American Chemical Society · 2002 · 10.1021/ja0262378

• Enantioselective Organocatalytic Indole Alkylations. Design of a New and Highly Effective Chiral Amine for Iminium Catalysis

  Journal of the American Chemical Society · 2002 · 10.1021/ja017255c

• New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction

  Journal of the American Chemical Society · 2000 · 10.1021/ja000092s

Current projects

No projects listed.