Akira Horii

Research interests

Publications

• Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

  Nature Communications · 2014 · 10.1038/ncomms4393

• Steroid Therapy during the Early Stage of Progressive IgA Nephropathy

  ˜The œNephron journals/Nephron journals · 2008 · 10.1159/000188848

• Cell surface Lactobacillus plantarum LA 318 glyceraldehyde-3-phosphate dehydrogenase (GAPDH) adheres to human colonic mucin

  Journal of Applied Microbiology · 2008 · 10.1111/j.1365-2672.2007.03679.x

• AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

  Oncogene · 2006 · 10.1038/sj.onc.1209494

• Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

  Journal of Human Genetics · 2005 · 10.1007/s10038-005-0235-y

• Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study

  Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 2005 · https://doi.org/10.1007/s00428-005-0039-7

• RNA Interference Targeting Aurora Kinase A Suppresses Tumor Growth and Enhances the Taxane Chemosensitivity in Human Pancreatic Cancer Cells

  Cancer Research · 2005 · 10.1158/0008-5472.can-04-3981

• Genome-wide profiling of promoter methylation in human

  Oncogene · 2005 · 10.1038/sj.onc.1209331

• Potential Tumor Suppressive Pathway Involving DUSP6/MKP-3 in Pancreatic Cancer

  American Journal Of Pathology · 2003 · 10.1016/s0002-9440(10)64315-5

• A Novel Target Gene, SKP2, within the 5p13 Amplicon That Is Frequently Detected in Small Cell Lung Cancers

  American Journal Of Pathology · 2002 · 10.1016/s0002-9440(10)64172-7

• A BAC-Based STS-Content Map Spanning a 35-Mb Region of Human Chromosome 1p35–p36

  Genomics · 2001 · 10.1006/geno.2001.6511

• The H-cadherin ( CDH13 ) gene is inactivated in human lung cancer

  Human Genetics · 1998 · 10.1007/s004390050790

• PTEN1 is frequently mutated in primary endometrial carcinomas

  Nature Genetics · 1997 · 10.1038/ng1097-143

• The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum.

  PubMed · 1997

• Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers.

  PubMed · 1994

• Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP).

  PubMed · 1993

• Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

  Proceedings of the National Academy of Sciences · 1992 · 10.1073/pnas.89.10.4452

• Frequent somatic mutations of the APC gene in human pancreatic cancer.

  PubMed · 1992

• The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.

  PubMed · 1992

• Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.

  PubMed · 1992

• Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

  Human Molecular Genetics · 1992 · 10.1093/hmg/1.8.559

• Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

  Human Molecular Genetics · 1992 · https://doi.org/10.1093/hmg/1.4.229

• Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

  PubMed · 1992

• Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

  Science · 1991 · https://doi.org/10.1126/science.1651563

• Identification of FAP Locus Genes from Chromosome 5q21

  Science · 1991 · https://doi.org/10.1126/science.1651562

Current projects

No projects listed.