Karen L. Lindsay

Research interests

Publications

• Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study

  The Lancet · 2014 · https://doi.org/10.1016/s0140-6736(14)61036-9

• Outcome of Sustained Virological Responders With Histologically Advanced Chronic Hepatitis C†,‡,§,¶

  Hepatology · 2010 · 10.1002/hep.23744

• Maintenance Peginterferon Therapy and Other Factors Associated With Hepatocellular Carcinoma in Patients With Advanced Hepatitis C

  Gastroenterology · 2010 · 10.1053/j.gastro.2010.11.050

• Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

  New England Journal of Medicine · 2008 · 10.1056/nejmoa0707615

• Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

  Gastroenterology · 2008 · 10.1053/j.gastro.2008.09.014

• Impact of Reducing Peginterferon Alfa-2a and Ribavirin Dose During Retreatment in Patients With Chronic Hepatitis C

  Gastroenterology · 2006 · 10.1053/j.gastro.2006.11.011

• Serum alpha-fetoprotein levels in patients with advanced hepatitis C: Results from the HALT-C Trial

  Journal of Hepatology · 2005 · 10.1016/j.jhep.2005.03.019

• Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests

  Hepatology · 2005 · 10.1002/hep.20772

• Peginterferon Alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment[1], [2] and [3] 1 2 3☆

  Gastroenterology · 2004 · 10.1053/j.gastro.2004.01.014

• Hepatitis C virus induces a mutator phenotype: Enhanced mutations of immunoglobulin and protooncogenes

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0303971101

• Establishment of B-Cell Lymphoma Cell Lines Persistently Infected with Hepatitis C Virus In Vivo and In Vitro: the Apoptotic Effects of Virus Infection

  Journal of Virology · 2003 · 10.1128/jvi.77.3.2134-2146.2003

• Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C

  Gastroenterology · 2002 · https://doi.org/10.1053/gast.2002.33023

• Adherence to combination therapy enhances sustained response in genotype-1–infected patients with chronic hepatitis C

  Gastroenterology · 2002 · https://doi.org/10.1053/gast.2002.35950

• A Randomized, Double–Blind Trial Comparing Pegylated Interferon Alfa–2B to Interferon Alfa–2B As Initial Treatment for Chronic Hepatitis C

  Hepatology · 2001 · 10.1053/jhep.2001.26371

• Complementary and alternative medicine in chronic liver disease

  Hepatology · 2001 · 10.1053/jhep.2001.27445

• Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease

  Hepatology · 1998 · 10.1002/hep.510270336

• Therapy of hepatitis C: Overview

  Hepatology · 1997 · 10.1002/hep.510260713

• Tolerance and efficacy of oral ribavirin treatment of chronic hepatitis C: A multicenter trial

  Hepatology · 1997 · 10.1002/hep.510260231

• Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.

  PubMed · 1997

• Application of Six Hepatitis C Virus Genotyping Systems to Sera from Chronic Hepatitis C Patients in the United States

  The Journal of Infectious Diseases · 1995 · 10.1093/infdis/171.2.281

• Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients.

  PubMed · 1994

• Pathological diagnosis of chronic hepatitis C: A multicenter comparative study with chronic hepatitis B

  Gastroenterology · 1993 · 10.1016/0016-5085(93)90432-c

• Neutrophil Cytoplasmic Antibodies: A Link Between Primary Sclerosing Cholangitis and Ulcerative Colitis

  Gastroenterology · 1991 · 10.1016/0016-5085(91)70028-v

• A Randomized, Controlled Trial of Interferon Alfa-2b Alone and after Prednisone Withdrawal for the Treatment of Chronic Hepatitis B

  New England Journal of Medicine · 1990 · 10.1056/nejm199008023230503

• Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

  New England Journal of Medicine · 1989 · https://doi.org/10.1056/nejm198911303212203

Current projects

No projects listed.