Esben Agerbo

Research interests

Publications

• Genomics yields biological and phenotypic insights into bipolar disorder

  Nature · 2025 · https://doi.org/10.1038/s41586-024-08468-9

• Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-022-01285-8

• Mapping genomic loci implicates genes and synaptic biology in schizophrenia

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04434-5

• Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00857-4

• A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

  Biological Psychiatry · 2021 · https://doi.org/10.1016/j.biopsych.2021.04.018

• Comorbidity within mental disorders: a comprehensive analysis based on 145 990 survey respondents from 27 countries

  Epidemiology and Psychiatric Sciences · 2020 · https://doi.org/10.1017/s2045796020000633

• Exploring Comorbidity Within Mental Disorders Among a Danish National Population

  JAMA Psychiatry · 2019 · https://doi.org/10.1001/jamapsychiatry.2018.3658

• Identification of common genetic risk variants for autism spectrum disorder

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0344-8

• Genome-wide association study identifies 30 loci associated with bipolar disorder

  Nature Genetics · 2019 · 10.1038/s41588-019-0397-8

• Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

  Cell · 2019 · 10.1016/j.cell.2019.11.020

• A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

  Nature Neuroscience · 2019 · https://doi.org/10.1038/s41593-018-0320-0

• GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

  American Journal of Psychiatry · 2019 · https://doi.org/10.1176/appi.ajp.2019.18080957

• The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

  Biological Psychiatry · 2019 · https://doi.org/10.1016/j.biopsych.2019.10.015

• A comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(19)32316-5

• Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

  Nature Genetics · 2018 · 10.1038/s41588-018-0059-2

• Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

  Science · 2018 · 10.1126/science.aad6469

• Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

  The American Journal of Human Genetics · 2018 · https://doi.org/10.1016/j.ajhg.2018.03.021

• Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

  Cell · 2018 · 10.1016/j.cell.2018.05.046

• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0090-3

• Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0269-7

• Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

  bioRxiv (Cold Spring Harbor Laboratory) · 2017 · https://doi.org/10.1101/173062

• Biological insights from 108 schizophrenia-associated genetic loci

  Nature · 2014 · https://doi.org/10.1038/nature13595

• Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.10.004

Current projects

No projects listed.