Samuel Klein

Research interests

Publications

• A multisociety Delphi consensus statement on new fatty liver disease nomenclature

  Annals of Hepatology · 2023 · https://doi.org/10.1016/j.aohep.2023.101133

• Why does obesity cause diabetes?

  Cell Metabolism · 2022 · https://doi.org/10.1016/j.cmet.2021.12.012

• Metabolically healthy obesity: facts and fantasies

  Journal of Clinical Investigation · 2019 · 10.1172/jci129186

• Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease

  Journal of Clinical Investigation · 2019 · 10.1172/jci134165

• Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity

  Cell Metabolism · 2016 · https://doi.org/10.1016/j.cmet.2016.02.005

• Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors’ Expert Forum

  Diabetes Care · 2015 · https://doi.org/10.2337/dc15-1081

• Interventions to Slow Aging in Humans: Are We Ready?

  Aging Cell · 2015 · 10.1111/acel.12338

• Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: The SCALE Maintenance randomized study

  International Journal of Obesity · 2013 · 10.1038/ijo.2013.120

• Energy balance and its components: implications for body weight regulation

  American Journal of Clinical Nutrition · 2012 · 10.3945/ajcn.112.036350

• Gastric bypass and banding equally improve insulin sensitivity and β cell function

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci64895

• A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

  Nature · 2012 · 10.1038/nature10986

• Assessing Adiposity

  Circulation · 2011 · https://doi.org/10.1161/cir.0b013e318233bc6a

• Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications

  Hepatology · 2009 · 10.1002/hep.23280

• Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0904944106

• The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake

  Cell Metabolism · 2008 · https://doi.org/10.1016/j.cmet.2007.11.012

• Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans

  Diabetes · 2007 · 10.2337/db06-1656

• Alterations in Adipose Tissue and Hepatic Lipid Kinetics in Obese Men and Women With Nonalcoholic Fatty Liver Disease

  Gastroenterology · 2007 · 10.1053/j.gastro.2007.11.038

• Human gut microbes associated with obesity

  Nature · 2006 · 10.1038/4441022a

• Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society

  American Journal of Clinical Nutrition · 2005 · 10.1093/ajcn/82.5.923

• Effect of Obesity and Insulin Resistance on Myocardial Substrate Metabolism and Efficiency in Young Women

  Circulation · 2004 · 10.1161/01.cir.0000127959.28627.f8

• Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0308291101

• Absence of an Effect of Liposuction on Insulin Action and Risk Factors for Coronary Heart Disease

  New England Journal of Medicine · 2004 · 10.1056/nejmoa033179

• Clinical Implications of Obesity With Specific Focus on Cardiovascular Disease

  Circulation · 2004 · 10.1161/01.cir.0000145546.97738.1e

• A Randomized Trial of a Low-Carbohydrate Diet for Obesity

  New England Journal of Medicine · 2003 · 10.1056/nejmoa022207

• An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein

  American Journal of Physiology-Endocrinology and Metabolism · 1997 · 10.1152/ajpendo.1997.273.1.e122

• Regulation of plasma fatty acid oxidation during low- and high-intensity exercise

  American Journal of Physiology-Endocrinology and Metabolism · 1997 · https://doi.org/10.1152/ajpendo.1997.272.6.e1065

• Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1

  The Journal of Clinical Endocrinology & Metabolism · 1997 · 10.1210/jcem.82.12.4450

• Adipose tissue leptin production and plasma leptin kinetics in humans

  Diabetes · 1996 · https://doi.org/10.2337/diabetes.45.7.984

• Adipose Tissue Leptin Production and Plasma Leptin Kinetics in Humans

  Diabetes · 1996 · https://doi.org/10.2337/diab.45.7.984

Current projects

No projects listed.