Francisco Lopera

Research interests

Publications

• Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

  Nature Medicine · 2024 · https://doi.org/10.1038/s41591-024-03209-x

• Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man

  Nature Medicine · 2023 · 10.1038/s41591-023-02318-3

• Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease

  Nature Medicine · 2023 · 10.1038/s41591-023-02476-4

• Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study

  The Lancet Neurology · 2020 · 10.1016/s1474-4422(20)30137-x

• Dementia in Latin America: Paving the way toward a regional action plan

  Alzheimer s & Dementia · 2020 · https://doi.org/10.1002/alz.12202

• World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

  Alzheimer s & Dementia · 2020 · https://doi.org/10.1002/alz.12123

• Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

  JAMA · 2020 · https://doi.org/10.1001/jama.2020.12134

• Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0611-3

• Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease

  JAMA Neurology · 2018 · 10.1001/jamaneurol.2017.4907

• Dementia in Latin America

  Neurology · 2018 · 10.1212/wnl.0000000000004897

• Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred

  JAMA Neurology · 2015 · 10.1001/jamaneurol.2014.3314

• Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences

  Cortex · 2015 · https://doi.org/10.1016/j.cortex.2015.05.022

• Symptom onset in autosomal dominant Alzheimer disease

  Neurology · 2014 · https://doi.org/10.1212/wnl.0000000000000596

• Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study

  The Lancet Neurology · 2012 · 10.1016/s1474-4422(12)70227-2

• Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

  The Lancet Neurology · 2012 · https://doi.org/10.1016/s1474-4422(12)70228-4

• Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study

  The Lancet Neurology · 2011 · 10.1016/s1474-4422(10)70323-9

• Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments

  Journal of Alzheimer s Disease · 2011 · 10.3233/jad-2011-0059

• Visual short-term memory binding deficits in familial Alzheimer’s disease

  Brain · 2010 · 10.1093/brain/awq148

• Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease

  Annals of Neurology · 2010 · 10.1002/ana.22105

• A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

  Molecular Psychiatry · 2010 · 10.1038/mp.2010.6

• A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome

  Neuron · 2010 · 10.1016/j.neuron.2010.04.030

• Meta‐analysis of genome‐wide linkage scans of attention deficit hyperactivity disorder

  American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2008 · 10.1002/ajmg.b.30878

• Attention-Deficit/Hyperactivity Disorder in a Population Isolate: Linkage to Loci at 4q13.2, 5q33.3, 11q22, and 17p11

  The American Journal of Human Genetics · 2004 · 10.1086/426154

• Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred

  Annals of Neurology · 2003 · 10.1002/ana.10636

• Clinical Features of Early-Onset Alzheimer Disease in a Large Kindred With an E280A Presenilin-1 Mutation

  JAMA · 1997 · 10.1001/jama.1997.03540340027028

• Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation

  JAMA · 1997 · 10.1001/jama.277.10.793

• The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

  Nature Genetics · 1995 · 10.1038/ng1095-219

Current projects

No projects listed.