Kristian Hveem

Research interests

Publications

• Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

  Nature Genetics · 2024 · https://doi.org/10.1038/s41588-024-01707-9

• Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-021-00990-0

• Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01233-6

• Genetic diversity fuels gene discovery for tobacco and alcohol use

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05477-4

• Cohort Profile Update: The HUNT Study, Norway

  International Journal of Epidemiology · 2022 · 10.1093/ije/dyac095

• A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00921-z

• SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe

  European Heart Journal · 2021 · https://doi.org/10.1093/eurheartj/ehab309

• Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.11.003

• Exome sequencing and characterization of 49,960 individuals in the UK Biobank

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2853-0

• Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(19)32519-x

• Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

  Nature Genetics · 2018 · 10.1038/s41588-018-0171-3

• Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study

  BMJ · 2018 · 10.1136/bmj.k4365

• Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0184-y

• Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

  Journal of the American College of Cardiology · 2017 · 10.1016/j.jacc.2016.11.056

• Exome-wide association study of plasma lipids in >300,000 individuals

  Nature Genetics · 2017 · 10.1038/ng.3977

• Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

  Nature Genetics · 2017 · 10.1038/ng.3985

• Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease

  JAMA · 2016 · 10.1001/jama.2016.5951

• Lifestyle Intervention in Gastroesophageal Reflux Disease

  Clinical Gastroenterology and Hepatology · 2015 · 10.1016/j.cgh.2015.04.176

• Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

  Nature Genetics · 2014 · 10.1038/ng.2926

• Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2915

• Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

  The American Journal of Human Genetics · 2014 · https://doi.org/10.1016/j.ajhg.2014.01.010

• Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2616

• Cohort Profile: The HUNT Study, Norway

  International Journal of Epidemiology · 2012 · https://doi.org/10.1093/ije/dys095

• Several common variants modulate heart rate, PR interval and QRS duration

  Nature Genetics · 2010 · 10.1038/ng.511

• A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.417

• A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

  Nature Genetics · 2009 · 10.1038/ng.353

• Identification of a new prostate cancer susceptibility locus on chromosome 8q24

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.444

• A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

  Nature · 2008 · https://doi.org/10.1038/nature06885

• Obesity and Estrogen as Risk Factors for Gastroesophageal Reflux Symptoms

  JAMA · 2003 · 10.1001/jama.290.1.66

Current projects

No projects listed.