David J. Adams

Research interests

Publications

• Advances in Xanthan Gum-Based Systems for the Delivery of Therapeutic Agents

  Pharmaceutics · 2023 · 10.3390/pharmaceutics15020402

• Trends in peptide drug discovery

  Nature Reviews Drug Discovery · 2021 · https://doi.org/10.1038/s41573-020-00135-8

• Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer

  Scientific Reports · 2016 · 10.1038/srep23179

• Micro-CT enables microlocalisation and quantification of Her2-targeted gold nanoparticles within tumour regions

  British Journal of Radiology · 2011 · 10.1259/bjr/42612922

• The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

  Angewandte Chemie International Edition · 2010 · 10.1002/anie.201000620

• Regulatory Changes in Neuroendocrine Stress-Integrative Circuitry Produced by a Variable Stress Paradigm

  Neuroendocrinology · 2008 · 10.1159/000126839

• Analgesic α-Conotoxins Vc1.1 and Rg1A Inhibit N-Type Calcium Channels in Rat Sensory Neurons via GABABReceptor Activation

  Journal of Neuroscience · 2008 · 10.1523/jneurosci.3594-08.2008

• The Doublecortin-Expressing Population in the Developing and Adult Brain Contains Multipotential Precursors in Addition to Neuronal-Lineage Cells

  Journal of Neuroscience · 2007 · 10.1523/jneurosci.5060-06.2007

• α-Selenoconotoxins, a New Class of Potent α7 Neuronal Nicotinic Receptor Antagonists

  Journal of Biological Chemistry · 2006 · 10.1074/jbc.m512419200

• μO-conotoxin MrVIB selectively blocks Na v 1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

  Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0601819103

• Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII

  Proceedings of the National Academy of Sciences · 2005 · 10.1073/pnas.0504613102

• Regulation of Neuronal Voltage-gated Sodium Channels by the Ubiquitin-Protein Ligases Nedd4 and Nedd4-2

  Journal of Biological Chemistry · 2004 · 10.1074/jbc.m402820200

• Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter

  Nature Neuroscience · 2001 · 10.1038/nn0901-902

• Novel ω-Conotoxins from Conus catus Discriminate among Neuronal Calcium Channel Subtypes

  Journal of Biological Chemistry · 2000 · 10.1074/jbc.m002252200

• Ion channels and regulation of intracellular calcium in vascular endothelial cells

  The FASEB Journal · 1989 · 10.1096/fasebj.3.12.2477294

• Taming the Ewald sum in the computer simulation of charged systems

  Journal of Computational Physics · 1987 · 10.1016/0021-9991(87)90076-3

• An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture

  Biochemical and Biophysical Research Communications · 1987 · 10.1016/0006-291x(87)91635-4

• Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells

  Tissue and Cell · 1987 · 10.1016/0040-8166(87)90015-2

• Ionic Currents in Molluscan Soma

  Annual Review of Neuroscience · 1980 · 10.1146/annurev.ne.03.030180.001041

• The permeability of endplate channels to monovalent and divalent metal cations.

  The Journal of General Physiology · 1980 · 10.1085/jgp.75.5.493

• The permeability of the endplate channel to organic cations in frog muscle.

  The Journal of General Physiology · 1980 · 10.1085/jgp.75.5.469

• The computer simulation of polar liquids

  Molecular Physics · 1979 · 10.1080/00268977900101751

• Computer simulation of ionic systems: The distorting effects of the boundary conditions

  Chemical Physics Letters · 1979 · 10.1016/0009-2614(79)80190-6

• Grand canonical ensemble Monte Carlo for a Lennard-Jones fluid

  Molecular Physics · 1975 · 10.1080/00268977500100221

• Chemical potential of hard-sphere fluids by Monte Carlo methods

  Molecular Physics · 1974 · 10.1080/00268977400102551

Current projects

No projects listed.