Danish Saleheen

Research interests

Publications

• Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01891-3

• Genomics and phenomics of body mass index reveals a complex disease network

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-35553-2

• Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis

  Circulation · 2019 · 10.1161/circulationaha.119.044362

• Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection

  Journal of the American College of Cardiology · 2019 · https://doi.org/10.1016/j.jacc.2018.09.085

• Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0222-9

• Association ofLPAVariants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies

  JAMA Cardiology · 2018 · https://doi.org/10.1001/jamacardio.2018.1470

• Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1701719

• Exome-wide association study of plasma lipids in >300,000 individuals

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3977

• Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3768

• ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

  Journal of the American College of Cardiology · 2017 · 10.1016/j.jacc.2017.02.030

• Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3874

• Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

  Science · 2016 · 10.1126/science.aad3517

• The genetic architecture of type 2 diabetes

  Nature · 2016 · 10.1038/nature18642

• Analysis of protein-coding genetic variation in 60,706 humans

  Nature · 2016 · 10.1038/nature19057

• Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

  Journal of the American College of Cardiology · 2016 · 10.1016/j.jacc.2016.03.520

• Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study

  The Lancet Diabetes & Endocrinology · 2015 · 10.1016/s2213-8587(15)00126-6

• A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

  Nature Genetics · 2015 · 10.1038/ng.3396

• A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

  EUR Research Repository (Erasmus University Rotterdam) · 2015

• Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

  The Lancet Diabetes & Endocrinology · 2015 · 10.1016/s2213-8587(15)00127-8

• Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3405

• Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

  Nature · 2014 · 10.1038/nature13917

• Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

  Nature Genetics · 2014 · 10.1038/ng.2897

• Identification of seven loci affecting mean telomere length and their association with disease

  Nature Genetics · 2013 · 10.1038/ng.2528

• Discovery and refinement of loci associated with lipid levels

  Nature Genetics · 2013 · 10.1038/ng.2797

• Large-scale association analysis identifies new risk loci for coronary artery disease

  Nature Genetics · 2012 · 10.1038/ng.2480

• Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

  The Lancet Neurology · 2012 · 10.1016/s1474-4422(12)70234-x

• Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

  Diabetes · 2011 · https://doi.org/10.2337/db11-0415

• A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

  Nature Genetics · 2011 · 10.1038/ng.782

• Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

  Nature Genetics · 2011 · 10.1038/ng.921

Current projects

No projects listed.