Cliona O’Farrelly

Research interests

Publications

• Smoking changes adaptive immunity with persistent effects

  Nature · 2024 · https://doi.org/10.1038/s41586-023-06968-8

• Autoantibodies against type I IFNs in patients with critical influenza pneumonia

  The Journal of Experimental Medicine · 2022 · https://doi.org/10.1084/jem.20220514

• Studying severe long COVID to understand post-infectious disorders beyond COVID-19

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01766-7

• Human genetic and immunological determinants of critical COVID-19 pneumonia

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04447-0

• Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity

  Annals of the American Thoracic Society · 2021 · https://doi.org/10.1513/annalsats.202009-1175oc

• Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection

  PLoS ONE · 2020 · https://doi.org/10.1371/journal.pone.0240784

• Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

  Nature Immunology · 2018 · https://doi.org/10.1038/s41590-018-0251-7

• Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis

  Cancer Immunology Research · 2018 · https://doi.org/10.1158/2326-6066.cir-18-0481

• Liver immunology and its role in inflammation and homeostasis

  Cellular and Molecular Immunology · 2016 · https://doi.org/10.1038/cmi.2016.3

• Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

  Immunity · 2012 · https://doi.org/10.1016/j.immuni.2012.06.016

• Clinical anxiety, cortisol and interleukin-6: Evidence for specificity in emotion–biology relationships

  Brain Behavior and Immunity · 2010 · https://doi.org/10.1016/j.bbi.2010.03.003

• CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

  The Journal of Immunology · 2009 · https://doi.org/10.4049/jimmunol.0901881

• Innate and adaptive lymphoid cells in the human liver

  Immunological Reviews · 2000 · https://doi.org/10.1034/j.1600-0528.2002.017416.x

• The Human Liver Contains Multiple Populations of NK Cells, T Cells, and CD3+CD56+ Natural T Cells with Distinct Cytotoxic Activities and Th1, Th2, and Th0 Cytokine Secretion Patterns

  The Journal of Immunology · 1999 · https://doi.org/10.4049/jimmunol.163.4.2314

• Resident human hepatitis lymphocytes are phenotypically different from circulating lymphocytes

  Journal of Hepatology · 1998 · https://doi.org/10.1016/s0168-8278(98)80206-7

Current projects

No projects listed.