Kingston H. G. Mills

Research interests

Publications

• IL-17 and IL-17-producing cells in protection versus pathology

  Nature reviews. Immunology · 2022 · 10.1038/s41577-022-00746-9

• Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner

  Biomaterials · 2020 · 10.1016/j.biomaterials.2020.119833

• Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

  Cell Metabolism · 2019 · 10.1016/j.cmet.2019.10.015

• Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

  Nature Immunology · 2018 · https://doi.org/10.1038/s41590-018-0251-7

• A guiding map for inflammation

  Nature Immunology · 2017 · https://doi.org/10.1038/ni.3790

• Immune checkpoints and their inhibition in cancer and infectious diseases

  European Journal of Immunology · 2017 · 10.1002/eji.201646875

• Trained immunity: A program of innate immune memory in health and disease

  Science · 2016 · https://doi.org/10.1126/science.aaf1098

• A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3806

• Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

  PLoS Pathogens · 2013 · 10.1371/journal.ppat.1003264

• TLR-dependent T cell activation in autoimmunity

  Nature reviews. Immunology · 2011 · 10.1038/nri3095

• Caspase-1–Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity

  The Journal of Immunology · 2011 · 10.4049/jimmunol.1003597

• Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

  Brain Behavior and Immunity · 2010 · 10.1016/j.bbi.2010.01.014

• Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

  Nature Immunology · 2010 · https://doi.org/10.1038/ni.1935

• T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

  Clinical & Experimental Immunology · 2010 · 10.1111/j.1365-2249.2010.04143.x

• Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

  Immunity · 2009 · https://doi.org/10.1016/j.immuni.2009.08.001

• CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

  The Journal of Immunology · 2009 · 10.4049/jimmunol.0901881

• Induction, function and regulation of IL‐17‐producing T cells

  European Journal of Immunology · 2008 · 10.1002/eji.200838535

• A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis

  The Journal of Experimental Medicine · 2006 · 10.1084/jem.20060285

• Suppression of Antitumor Immunity by IL-10 and TGF-β-Producing T Cells Infiltrating the Growing Tumor: Influence of Tumor Environment on the Induction of CD4+ and CD8+ Regulatory T Cells

  The Journal of Immunology · 2006 · 10.4049/jimmunol.177.2.896

• TLR4 Mediates Vaccine-Induced Protective Cellular Immunity to Bordetella pertussis : Role of IL-17-Producing T Cells

  The Journal of Immunology · 2006 · 10.4049/jimmunol.177.11.7980

• Regulatory T cells: friend or foe in immunity to infection?

  Nature reviews. Immunology · 2004 · 10.1038/nri1485

• Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases

  Trends in Immunology · 2002 · 10.1016/s1471-4906(02)02288-3

• Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells

  The Journal of Experimental Medicine · 2002 · 10.1084/jem.20011288

• Cell-mediated immunity to Bordetella pertussis: role of Th1 cells in bacterial clearance in a murine respiratory infection model

  Infection and Immunity · 1993 · 10.1128/iai.61.2.399-410.1993

• Long-Term Ecosystem Stress: The Effects of Years of Experimental Acidification on a Small Lake

  Science · 1985 · 10.1126/science.228.4706.1395

Current projects

No projects listed.