Timothy A. Ryan

Research interests

Publications

• SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

  Neuron · 2019 · https://doi.org/10.1016/j.neuron.2019.05.002

• INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

  The Journal of Cell Biology · 2017 · https://doi.org/10.1083/jcb.201709111

• GLUT4 Mobilization Supports Energetic Demands of Active Synapses

  Neuron · 2017 · https://doi.org/10.1016/j.neuron.2016.12.020

• Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages

  Cell · 2017 · https://doi.org/10.1016/j.cell.2017.08.041

• Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

  Cell · 2014 · https://doi.org/10.1016/j.cell.2013.12.042

• α2δ expression sets presynaptic calcium channel abundance and release probability

  Nature · 2012 · https://doi.org/10.1038/nature11033

• A Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle Endocytosis

  Science · 2007 · https://doi.org/10.1126/science.1140621

• Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0707574105

• Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

  Nature · 2004 · https://doi.org/10.1038/nature02896

• Actin has a molecular scaffolding, not propulsive, role in presynaptic function

  Nature Neuroscience · 2003 · https://doi.org/10.1038/nn1002

• Synaptic Vesicle Mobilization Is Regulated by Distinct Synapsin I Phosphorylation Pathways at Different Frequencies

  Neuron · 2003 · https://doi.org/10.1016/s0896-6273(03)00151-x

• Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8+ T cell activation and cytolysis

  European Journal of Immunology · 2003 · https://doi.org/10.1002/eji.200324270

• Calcium accelerates endocytosis of vSNAREs at hippocampal synapses

  Nature Neuroscience · 2001 · https://doi.org/10.1038/83949

• Synapsin dispersion and reclustering during synaptic activity

  Nature Neuroscience · 2001 · https://doi.org/10.1038/nn756

• The Use of pHluorins for Optical Measurements of Presynaptic Activity

  Biophysical Journal · 2000 · https://doi.org/10.1016/s0006-3495(00)76468-x

• Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system

  Nature Cell Biology · 2000 · https://doi.org/10.1038/35008615

• The kinetics of synaptic vesicle recycling measured at single presynaptic boutons

  Neuron · 1993 · https://doi.org/10.1016/0896-6273(93)90081-2

• Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria

  Nature · 1993 · https://doi.org/10.1038/364639a0

• Symptoms, adverse effects, and complications associated with dobutamine stress echocardiography. Experience in 1118 patients.

  Circulation · 1993 · https://doi.org/10.1161/01.cir.88.1.15

• Mechanism for Regulating Cell Surface Distribution of Na + ,K + -ATPase in Polarized Epithelial Cells

  Science · 1991 · https://doi.org/10.1126/science.1658934

• Echocardiographic detection of coronary artery disease during dobutamine infusion.

  Circulation · 1991 · https://doi.org/10.1161/01.cir.83.5.1605

Current projects

No projects listed.