Hang Yin

Research interests

Publications

• Magnetic sensitivity of cryptochrome 4 from a migratory songbird

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03618-9

• SARS-CoV-2 spike protein interacts with and activates TLR41

  Cell Research · 2021 · 10.1038/s41422-021-00495-9

• Small-Molecule Modulators of Toll-like Receptors

  Accounts of Chemical Research · 2020 · 10.1021/acs.accounts.9b00631

• Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop

  Journal of Extracellular Vesicles · 2019 · 10.1080/20013078.2019.1684862

• Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles

  Stem Cells Translational Medicine · 2017 · 10.1002/sctm.17-0055

• Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility

  Journal of Extracellular Vesicles · 2017 · 10.1080/20013078.2017.1396823

• Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

  Proceedings of the National Academy of Sciences · 2016 · https://doi.org/10.1073/pnas.1602070113

• HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia

  Cell Reports · 2016 · 10.1016/j.celrep.2016.09.076

• Drugging Membrane Protein Interactions

  Annual Review of Biomedical Engineering · 2016 · 10.1146/annurev-bioeng-092115-025322

• A magnetic protein biocompass

  Nature Materials · 2015 · 10.1038/nmat4484

• DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling

  Molecular Psychiatry · 2015 · 10.1038/mp.2014.177

• Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

  Science Signaling · 2015 · 10.1126/scisignal.2005965

• Pharmacological characterization of the opioid inactive isomers (+)‐naltrexone and (+)‐naloxone as antagonists of toll‐like receptor 4

  British Journal of Pharmacology · 2015 · 10.1111/bph.13394

• Exosomes and Microvesicles: Identification and Targeting By Particle Size and Lipid Chemical Probes

  ChemBioChem · 2014 · 10.1002/cbic.201400043

• Discovery of Small‐Molecule Inhibitors of the TLR1/TLR2 Complex

  Angewandte Chemie International Edition · 2012 · 10.1002/anie.201204910

• Morphine activates neuroinflammation in a manner parallel to endotoxin

  Proceedings of the National Academy of Sciences · 2012 · https://doi.org/10.1073/pnas.1200130109

• Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

  Journal of Neuroscience · 2012 · 10.1523/jneurosci.0684-12.2012

• Toll‐like receptor 4 in CNS pathologies

  Journal of Neurochemistry · 2010 · 10.1111/j.1471-4159.2010.06736.x

• Evidence that opioids may have toll-like receptor 4 and MD-2 effects

  Brain Behavior and Immunity · 2009 · https://doi.org/10.1016/j.bbi.2009.08.004

• Computational Design of Peptides That Target Transmembrane Helices

  Science · 2007 · 10.1126/science.1136782

• Terphenyl-Based Bak BH3 α-Helical Proteomimetics as Low-Molecular-Weight Antagonists of Bcl-x L

  Journal of the American Chemical Society · 2005 · 10.1021/ja050122x

• Strategies for Targeting Protein–Protein Interactions With Synthetic Agents

  Angewandte Chemie International Edition · 2005 · https://doi.org/10.1002/anie.200461786

• Terphenyl‐Based Helical Mimetics That Disrupt the p53/HDM2 Interaction

  Angewandte Chemie International Edition · 2005 · 10.1002/anie.200462316

• Design and Application of an α‐Helix‐Mimetic Scaffold Based on an Oligoamide‐Foldamer Strategy: Antagonism of the Bak BH3/Bcl‐xL Complex

  Angewandte Chemie International Edition · 2003 · 10.1002/anie.200390154

• Development of a Potent Bcl-x L Antagonist Based on α-Helix Mimicry

  Journal of the American Chemical Society · 2002 · 10.1021/ja026861k

Current projects

No projects listed.