Daron M. Standley

Research interests

Publications

• Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota

  Nature Cell Biology · 2023 · 10.1038/s41556-023-01145-5

• An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

  Cell · 2021 · 10.1016/j.cell.2021.05.032

• Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells

  Nature Medicine · 2021 · 10.1038/s41591-021-01326-5

• MAFFT-DASH: integrated protein sequence and structural alignment

  Nucleic Acids Research · 2019 · https://doi.org/10.1093/nar/gkz342

• TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a

  Nucleic Acids Research · 2017 · 10.1093/nar/gkx064

• Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense

  Nature Immunology · 2017 · 10.1038/ni.3767

• A simple method to control over-alignment in the MAFFT multiple sequence alignment program

  Bioinformatics · 2016 · https://doi.org/10.1093/bioinformatics/btw108

• Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA

  The Journal of Experimental Medicine · 2016 · 10.1084/jem.20151289

• Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

  Cell · 2015 · 10.1016/j.cell.2015.04.029

• Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

  Nature Communications · 2014 · 10.1038/ncomms4492

• Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1312717110

• Akirin2 is critical for inducing inflammatory genes by bridging IκB‐ζ and the SWI/SNF complex

  The EMBO Journal · 2014 · 10.15252/embj.201488447

• MAFFT: Iterative Refinement and Additional Methods

  Methods in molecular biology · 2013 · https://doi.org/10.1007/978-1-62703-646-7_8

• Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation

  Cell · 2013 · 10.1016/j.cell.2013.04.034

• Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions

  Proteins Structure Function and Bioinformatics · 2013 · 10.1002/prot.24356

• MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

  Molecular Biology and Evolution · 2013 · https://doi.org/10.1093/molbev/mst010

• The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1

  Nature Immunology · 2011 · 10.1038/ni.2137

• Protein Data Bank Japan (PDBj): maintaining a structural data archive and resource description framework format

  Nucleic Acids Research · 2011 · 10.1093/nar/gkr811

• A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

  Journal of Clinical Investigation · 2011 · 10.1172/jci58414

• Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

  Journal of Molecular Biology · 2011 · 10.1016/j.jmb.2011.09.031

• EPSVR and EPMeta: prediction of antigenic epitopes using support vector regression and multiple server results

  BMC Bioinformatics · 2010 · 10.1186/1471-2105-11-381

• The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

  Nature Immunology · 2010 · https://doi.org/10.1038/ni.1920

• Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

  Nature · 2009 · 10.1038/nature07924

• Outcome of a Workshop on Applications of Protein Models in Biomedical Research

  Structure · 2009 · 10.1016/j.str.2008.12.014

• A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3

  The Journal of Experimental Medicine · 2009 · 10.1084/jem.20091703

Current projects

No projects listed.