Makoto M. Taketo

Research interests

Publications

• Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1856-1

• Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.05.028

• AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

  Nature Cell Biology · 2017 · https://doi.org/10.1038/ncb3563

• Dclk1 distinguishes between tumor and normal stem cells in the intestine

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2481

• Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

  Cell · 2012 · https://doi.org/10.1016/j.cell.2012.12.012

• Increased Wingless ( Wnt ) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1101553108

• Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

  Cell · 2011 · https://doi.org/10.1016/j.cell.2011.09.053

• Subtypes of medulloblastoma have distinct developmental origins

  Nature · 2010 · https://doi.org/10.1038/nature09587

• Wnt/β-catenin signaling controls development of the blood–brain barrier

  The Journal of Cell Biology · 2008 · https://doi.org/10.1083/jcb.200806024

• Wnt signalling induces maturation of Paneth cells in intestinal crypts

  Nature Cell Biology · 2005 · https://doi.org/10.1038/ncb1240

• Canonical Wnt/β-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes

  Developmental Cell · 2005 · https://doi.org/10.1016/j.devcel.2005.02.013

• Interactions between Sox9 and β-catenin control chondrocyte differentiation

  Genes & Development · 2004 · https://doi.org/10.1101/gad.1171104

• Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps.

  PubMed · 2002

• Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene

  The EMBO Journal · 2002 · https://doi.org/10.1093/emboj/cdf516

• Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene

  The EMBO Journal · 1999 · https://doi.org/10.1093/emboj/18.21.5931

• Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part I)

  JNCI Journal of the National Cancer Institute · 1998 · https://doi.org/10.1093/jnci/90.20.1529

• Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

  Cell · 1996 · https://doi.org/10.1016/s0092-8674(00)81988-1

• TGF-β Receptor Type II Deficiency Results in Defects of Yolk Sac Hematopoiesis and Vasculogenesis

  Developmental Biology · 1996 · https://doi.org/10.1006/dbio.1996.0259

Current projects

No projects listed.