Guillaume Bourque

Research interests

Publications

• GA4GH: International policies and standards for data sharing across genomic research and healthcare

  Cell Genomics · 2021 · https://doi.org/10.1016/j.xgen.2021.100029

• Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0562-0

• Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-17186-5

• Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types

  Nature Metabolism · 2019 · https://doi.org/10.1038/s42255-019-0152-6

• Ten things you should know about transposable elements

  Genome biology · 2018 · https://doi.org/10.1186/s13059-018-1577-z

• MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

  Nucleic Acids Research · 2018 · https://doi.org/10.1093/nar/gky310

• High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies

  The American Journal of Human Genetics · 2017 · https://doi.org/10.1016/j.ajhg.2017.09.008

• Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.10.026

• The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.10.042

• The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.11.007

• Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms13555

• The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

  Nature Structural & Molecular Biology · 2014 · https://doi.org/10.1038/nsmb.2799

• Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2936

• The Majority of Primate-Specific Regulatory Sequences Are Derived from Transposable Elements

  PLoS Genetics · 2013 · https://doi.org/10.1371/journal.pgen.1003504

• Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAs

  PLoS Genetics · 2013 · https://doi.org/10.1371/journal.pgen.1003470

• K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

  Acta Neuropathologica · 2012 · 10.1007/s00401-012-0998-0

• CTCF-mediated functional chromatin interactome in pluripotent cells

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.857

• Transposable elements have rewired the core regulatory network of human embryonic stem cells

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.600

• An oestrogen-receptor-α-bound human chromatin interactome

  Nature · 2009 · https://doi.org/10.1038/nature08497

• Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

  Cell · 2008 · https://doi.org/10.1016/j.cell.2008.04.043

• Evolution of the mammalian transcription factor binding repertoire via transposable elements

  Genome Research · 2008 · https://doi.org/10.1101/gr.080663.108

• Whole-Genome Cartography of Estrogen Receptor α Binding Sites

  PLoS Genetics · 2007 · https://doi.org/10.1371/journal.pgen.0030087

• Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells

  Cell stem cell · 2007 · https://doi.org/10.1016/j.stem.2007.08.004

• Initial sequence and comparative analysis of the cat genome

  Genome Research · 2007 · https://doi.org/10.1101/gr.6380007

• The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1760

• Dynamics of Mammalian Chromosome Evolution Inferred from Multispecies Comparative Maps

  Science · 2005 · https://doi.org/10.1126/science.1111387

• Genome-scale evolution: reconstructing gene orders in the ancestral species.

  PubMed · 2002

Current projects

No projects listed.