Klemens Ruprecht

Research interests

Publications

• Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management

  Journal of Neurology · 2023 · https://doi.org/10.1007/s00415-023-11910-z

• Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis

  Journal of Neurology · 2023 · https://doi.org/10.1007/s00415-023-11634-0

• Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients

  Journal of Neuroinflammation · 2022 · https://doi.org/10.1186/s12974-021-02339-0

• Interleukin-6 Receptor Blockade in Treatment-Refractory MOG-IgG–Associated Disease and Neuromyelitis Optica Spectrum Disorders

  Neurology Neuroimmunology & Neuroinflammation · 2021 · https://doi.org/10.1212/nxi.0000000000001100

• Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

  Journal of Neuroinflammation · 2020 · https://doi.org/10.1186/s12974-020-01824-2

• Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation

  NeuroImage Clinical · 2019 · 10.1016/j.nicl.2019.102003

• MOG encephalomyelitis: international recommendations on diagnosis and antibody testing

  Journal of Neuroinflammation · 2018 · https://doi.org/10.1186/s12974-018-1144-2

• Racial differences in neuromyelitis optica spectrum disorder

  Neurology · 2018 · 10.1212/wnl.0000000000006574

• Apheresis therapies for NMOSD attacks

  Neurology Neuroimmunology & Neuroinflammation · 2018 · https://doi.org/10.1212/nxi.0000000000000504

• Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

  Journal of Neurology Neurosurgery & Psychiatry · 2017 · https://doi.org/10.1136/jnnp-2017-315603

• Evaluation of Cognitive Deficits and Structural Hippocampal Damage in Encephalitis With Leucine-Rich, Glioma-Inactivated 1 Antibodies

  JAMA Neurology · 2017 · 10.1001/jamaneurol.2016.4226

• Bortezomib for treatment of therapy-refractory anti-NMDA receptor encephalitis

  Neurology · 2016 · 10.1212/wnl.0000000000003536

• MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

  Journal of Neuroinflammation · 2016 · https://doi.org/10.1186/s12974-016-0719-z

• MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

  Journal of Neuroinflammation · 2016 · https://doi.org/10.1186/s12974-016-0718-0

• MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

  Journal of Neuroinflammation · 2016 · https://doi.org/10.1186/s12974-016-0720-6

• MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

  Journal of Neuroinflammation · 2016 · https://doi.org/10.1186/s12974-016-0717-1

• Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

  Annals of Neurology · 2015 · https://doi.org/10.1002/ana.24554

• Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis

  PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0066151

• A blood based 12-miRNA signature of Alzheimer disease patients

  Genome biology · 2013 · https://doi.org/10.1186/gb-2013-14-7-r78

• Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis

  Neurology · 2012 · https://doi.org/10.1212/wnl.0b013e3182648bc8

• Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

  Journal of Neuroinflammation · 2012 · https://doi.org/10.1186/1742-2094-9-14

• Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease

  Multiple Sclerosis Journal · 2012 · 10.1177/1352458512441381

• A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus

  Journal of Virology · 2011 · 10.1128/jvi.02602-10

• Toward the blood-borne miRNome of human diseases

  Nature Methods · 2011 · https://doi.org/10.1038/nmeth.1682

• Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: Results from 211 lumbar punctures

  Journal of the Neurological Sciences · 2011 · https://doi.org/10.1016/j.jns.2011.03.038

• Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

  Journal of the Neurological Sciences · 2010 · https://doi.org/10.1016/j.jns.2010.07.011

• Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

  Journal of Neuroinflammation · 2010 · https://doi.org/10.1186/1742-2094-7-52

• Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls

  PLoS ONE · 2009 · 10.1371/journal.pone.0007440

Current projects

No projects listed.