Botond Penke

Research interests

Publications

• Oligomerization and Conformational Change Turn Monomeric β-Amyloid and Tau Proteins Toxic: Their Role in Alzheimer’s Pathogenesis

  Molecules · 2020 · https://doi.org/10.3390/molecules25071659

• β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View

  Molecules · 2017 · https://doi.org/10.3390/molecules22101692

• The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases

  Current Neuropharmacology · 2017 · https://doi.org/10.2174/1570159x15666170529104323

• TLR2 Is a Primary Receptor for Alzheimer’s Amyloid β Peptide To Trigger Neuroinflammatory Activation

  The Journal of Immunology · 2011 · https://doi.org/10.4049/jimmunol.1101121

• Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms

  Journal of Biological Chemistry · 2011 · https://doi.org/10.1074/jbc.m110.182329

• Interactions of Pathological Hallmark Proteins

  Journal of Biological Chemistry · 2011 · https://doi.org/10.1074/jbc.m111.243907

• Functionalization of gold nanoparticles with amino acid, β-amyloid peptides and fragment

  Colloids and Surfaces B Biointerfaces · 2010 · https://doi.org/10.1016/j.colsurfb.2010.07.011

• Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

  Journal of Neuroscience · 2009 · https://doi.org/10.1523/jneurosci.5215-08.2009

• Role of the Toll-Like Receptor 4 in Neuroinflammation in Alzheimer’s Disease

  Cellular Physiology and Biochemistry · 2007 · https://doi.org/10.1159/000110455

• Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease

  Neurochemistry International · 2006 · https://doi.org/10.1016/j.neuint.2006.08.012

• Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice

  Neurobiology of Disease · 2006 · https://doi.org/10.1016/j.nbd.2006.04.013

• LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide

  Brain · 2005 · https://doi.org/10.1093/brain/awh531

• Kynurenine metabolism in multiple sclerosis

  Acta Neurologica Scandinavica · 2005 · https://doi.org/10.1111/j.1600-0404.2005.00442.x

• Amyloid β‐peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

  Journal of Peptide Science · 2004 · https://doi.org/10.1002/psc.573

• Binding Sites of Amyloid β-Peptide in Cell Plasma Membrane and Implications for Alzheimers Disease

  Current Protein and Peptide Science · 2004 · https://doi.org/10.2174/1389203043486937

• The LPS receptor (CD14) links innate immunity with Alzheimer's disease

  The FASEB Journal · 2003 · https://doi.org/10.1096/fj.03-0364fje

• Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells

  Brain Research Bulletin · 2003 · https://doi.org/10.1016/j.brainresbull.2003.09.011

• Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats

  Neuroscience · 2003 · https://doi.org/10.1016/s0306-4522(03)00198-2

• β‐Amyloid neurotoxicity is mediated by a glutamate‐triggered excitotoxic cascade in rat nucleus basalis

  European Journal of Neuroscience · 2000 · https://doi.org/10.1046/j.1460-9568.2000.00164.x

• Mechanisms of ß-Amyloid Neurotoxicity: Perspectives of Pharmacotherapy

  Reviews in the Neurosciences · 2000 · https://doi.org/10.1515/revneuro.2000.11.4.329

• Immunohistochemical visualization of a metabotropic glutamate receptor

  Neuroreport · 1993 · https://doi.org/10.1097/00001756-199303000-00014

• The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats

  Brain Research · 1992 · https://doi.org/10.1016/0006-8993(92)91176-f

• Antisera to gamma-aminobutyric acid. I. Production and characterization using a new model system.

  Journal of Histochemistry & Cytochemistry · 1985 · https://doi.org/10.1177/33.3.3973378

• Antisera to gamma-aminobutyric acid. II. Immunocytochemical application to the central nervous system.

  Journal of Histochemistry & Cytochemistry · 1985 · https://doi.org/10.1177/33.3.2579123

• A new acid hydrolysis method for determining tryptophan in peptides and proteins

  Analytical Biochemistry · 1974 · https://doi.org/10.1016/0003-2697(74)90129-8

Current projects

No projects listed.