Rachel M. Freathy

Research interests

Publications

• Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour

  Nature Communications · 2019 · 10.1038/s41467-019-09576-1

• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

  Science Advances · 2019 · 10.1126/sciadv.aaw3095

• Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

  Nature Communications · 2019 · 10.1038/s41467-018-08259-7

• Using genetics to understand the causal influence of higher BMI on depression

  International Journal of Epidemiology · 2018 · 10.1093/ije/dyy223

• Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

  Human Molecular Genetics · 2018 · https://doi.org/10.1093/hmg/ddx429

• Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

  JAMA · 2016 · https://doi.org/10.1001/jama.2016.1975

• Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

  BMJ · 2016 · 10.1136/bmj.i582

• Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

  Aging · 2016 · 10.18632/aging.100930

• Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

  Diabetes · 2016 · 10.2337/db15-1671

• Gene–obesogenic environment interactions in the UK Biobank study

  International Journal of Epidemiology · 2016 · 10.1093/ije/dyw337

• Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

  PLoS Genetics · 2016 · https://doi.org/10.1371/journal.pgen.1006125

• A novel common variant in DCST2 is associated with length in early life and height in adulthood

  Human Molecular Genetics · 2014 · https://doi.org/10.1093/hmg/ddu510

• Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

  PLoS Genetics · 2014 · https://doi.org/10.1371/journal.pgen.1004123

• A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

  PLoS Genetics · 2013 · https://doi.org/10.1371/journal.pgen.1003266

• Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.567

• A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

  Human Molecular Genetics · 2009 · 10.1093/hmg/ddp216

• Genome-wide association analysis identifies 20 loci that influence adult height

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.121

• Common variants near MC4R are associated with fat mass, weight and risk of obesity

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.140

• Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.120

• Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI

  Diabetes · 2008 · 10.2337/db07-1466

• FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians

  Diabetologia · 2008 · 10.1007/s00125-008-1186-6

• A common variant of HMGA2 is associated with adult and childhood height in the general population

  Nature Genetics · 2007 · 10.1038/ng2121

• Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

  Science · 2007 · https://doi.org/10.1126/science.1142364

• A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

  Science · 2007 · https://doi.org/10.1126/science.1141634

Current projects

No projects listed.