Michael P. Weekes

Research interests

Publications

• Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04474-x

• Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

  Immunity · 2021 · 10.1016/j.immuni.2021.05.010

• Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03412-7

• SARS-CoV-2 evolution during treatment of chronic infection

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03291-y

• Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03739-1

• Covid-19: should the public wear face masks?

  BMJ · 2020 · 10.1136/bmj.m1442

• Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

  The Lancet Infectious Diseases · 2020 · 10.1016/s1473-3099(20)30562-4

• Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation

  Cell Metabolism · 2019 · 10.1016/j.cmet.2019.06.003

• Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax

  Science · 2018 · 10.1126/science.aan1078

• High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

  Cell Host & Microbe · 2018 · 10.1016/j.chom.2018.07.011

• High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

  Cell Host & Microbe · 2018 · 10.1016/j.chom.2018.07.011

• Improved Ribo-seq enables identification of cryptic translation events

  Nature Methods · 2018 · 10.1038/nmeth.4631

• NOTCH1 mediates a switch between two distinct secretomes during senescence

  Nature Cell Biology · 2016 · 10.1038/ncb3397

• A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion

  Science · 2015 · 10.1126/science.aaa3526

• Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

  Cell Host & Microbe · 2015 · 10.1016/j.chom.2015.09.003

• Human cytomegalovirus: taking the strain

  Medical Microbiology and Immunology · 2015 · 10.1007/s00430-015-0411-4

• A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion

  Science · 2015 · 10.1126/science.aaa3526

• Human cytomegalovirus: taking the strain

  Medical Microbiology and Immunology · 2015 · 10.1007/s00430-015-0411-4

• Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation

  PLoS Pathogens · 2014 · 10.1371/journal.ppat.1004058

• Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation

  PLoS Pathogens · 2014 · 10.1371/journal.ppat.1004058

• Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

  Cell · 2014 · 10.1016/j.cell.2014.04.028

• Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

  Science · 2013 · 10.1126/science.1235047

• Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

  Science · 2013 · 10.1126/science.1235047

• Recognition of HLA‐A3 and HLA‐A11 by KIR3DL2 is peptide‐specific

  European Journal of Immunology · 2004 · 10.1002/eji.200425089

• Identification of Naive or Antigen-Experienced Human CD8+ T Cells by Expression of Costimulation and Chemokine Receptors: Analysis of the Human Cytomegalovirus-Specific CD8+ T Cell Response

  The Journal of Immunology · 2002 · 10.4049/jimmunol.168.11.5455

• Human CD28−CD8+ T Cells Contain Greatly Expanded Functional Virus-Specific Memory CTL Clones

  The Journal of Immunology · 1999 · 10.4049/jimmunol.162.12.7569

• Human CD28−CD8+ T Cells Contain Greatly Expanded Functional Virus-Specific Memory CTL Clones

  The Journal of Immunology · 1999 · 10.4049/jimmunol.162.12.7569

• The Memory Cytotoxic T-Lymphocyte (CTL) Response to Human Cytomegalovirus Infection Contains Individual Peptide-Specific CTL Clones That Have Undergone Extensive Expansion In Vivo

  Journal of Virology · 1999 · 10.1128/jvi.73.3.2099-2108.1999

• Human Virus-Specific CD8+ CTL Clones Revert from CD45ROhigh to CD45RAhigh In Vivo: CD45RAhighCD8+ T Cells Comprise Both Naive and Memory Cells

  The Journal of Immunology · 1999 · 10.4049/jimmunol.162.12.7080

• The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

  Journal of Virology · 1996 · https://doi.org/10.1128/jvi.70.11.7569-7579.1996

• Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis

  The Journal of Pathology · 1995 · 10.1002/path.1711770310

Current projects

No projects listed.