Vincent J. Gnanapragasam

Research interests

Publications

• Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

  New England Journal of Medicine · 2023 · https://doi.org/10.1056/nejmoa2214122

• Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer

  Cancer Cell · 2022 · https://doi.org/10.1016/j.ccell.2022.11.001

• Resolving the immune landscape of human prostate at a single-cell level in health and cancer

  Cell Reports · 2021 · 10.1016/j.celrep.2021.110132

• Extensive heterogeneity in somatic mutation and selection in the human bladder

  Science · 2020 · 10.1126/science.aba8347

• Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received

  European Urology · 2019 · 10.1016/j.eururo.2019.10.030

• Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received

  European Urology · 2019 · 10.1016/j.eururo.2019.10.030

• Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0086-z

• Mutational signatures of ionizing radiation in second malignancies

  Nature Communications · 2016 · 10.1038/ncomms12605

• Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

  Nature · 2016 · https://doi.org/10.1038/nature19353

• Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

  EBioMedicine · 2015 · 10.1016/j.ebiom.2015.07.017

• Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

  Nature Communications · 2015 · 10.1038/ncomms7605

• Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3221

• Defining the learning curve for multiparametric magnetic resonance imaging ( MRI ) of the prostate using MRI ‐transrectal ultrasonography ( TRUS ) fusion‐guided transperineal prostate biopsies as a validation tool

  British Journal of Urology · 2014 · 10.1111/bju.12892

• Definitions of terms, processes and a minimum dataset for transperineal prostate biopsies: a standardization approach of the G insburg S tudy G roup for E nhanced P rostate D iagnostics

  British Journal of Urology · 2013 · 10.1111/bju.12132

• Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development

  Oncogene · 2003 · 10.1038/sj.onc.1206342

• Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development

  Oncogene · 2003 · 10.1038/sj.onc.1206342

• Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer

  British Journal of Cancer · 2001 · 10.1054/bjoc.2001.2179

Current projects

No projects listed.