Chris Wallace

Research interests

Publications

• Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches

  The American Journal of Human Genetics · 2022 · 10.1016/j.ajhg.2022.04.001

• Mendelian randomization

  Nature Reviews Methods Primers · 2022 · https://doi.org/10.1038/s43586-021-00092-5

• A more accurate method for colocalisation analysis allowing for multiple causal variants

  PLoS Genetics · 2021 · 10.1371/journal.pgen.1009440

• Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses

  PLoS Genetics · 2020 · 10.1371/journal.pgen.1008720

• Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.09.037

• Correction: Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms8741

• Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3245

• Widespread seasonal gene expression reveals annual differences in human immunity and physiology

  Nature Communications · 2015 · 10.1038/ncomms8000

• Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

  PLoS Genetics · 2014 · https://doi.org/10.1371/journal.pgen.1004383

• A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

  Diabetes · 2014 · 10.2337/db13-1777

• Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

  Diabetes · 2011 · 10.2337/db10-1656

• Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

  Nature Genetics · 2011 · 10.1038/ng.998

• Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

  Nature Genetics · 2011 · 10.1038/ng.970

• Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

  Nature · 2010 · 10.1038/nature08979

• A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

  Nature · 2010 · 10.1038/nature09386

• Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

  PLoS Genetics · 2009 · 10.1371/journal.pgen.1000504

• Genome-wide association study identifies eight loci associated with blood pressure

  Nature Genetics · 2009 · 10.1038/ng.361

• Vascularized Groin Lymph Node Transfer Using the Wrist as a Recipient Site for Management of Postmastectomy Upper Extremity Lymphedema

  Plastic & Reconstructive Surgery · 2009 · 10.1097/prs.0b013e31819e6529

• The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

  Nature Genetics · 2009 · 10.1038/ng.493

• SLC2A9 Is a High-Capacity Urate Transporter in Humans

  PLoS Medicine · 2008 · 10.1371/journal.pmed.0050197

• Genome-wide association analysis identifies 20 loci that influence adult height

  Nature Genetics · 2008 · 10.1038/ng.121

• Common variants near MC4R are associated with fat mass, weight and risk of obesity

  Nature Genetics · 2008 · 10.1038/ng.140

• Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

  The American Journal of Human Genetics · 2008 · 10.1016/j.ajhg.2007.11.001

• Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  Nature Genetics · 2007 · 10.1038/ng2068

• Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis of impulsive behaviour

  Psychopharmacology · 1999 · 10.1007/pl00005494

Current projects

No projects listed.