John Trowsdale

Research interests

Publications

• Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans

  Cell Reports · 2016 · https://doi.org/10.1016/j.celrep.2016.04.005

• NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

  Blood · 2013 · https://doi.org/10.1182/blood-2012-10-459545

• Major Histocompatibility Complex Genomics and Human Disease

  Annual Review of Genomics and Human Genetics · 2013 · https://doi.org/10.1146/annurev-genom-091212-153455

• Nomenclature for Factors of the HLA System, 2026

  Tissue Antigens · 2010 · https://doi.org/10.1111/j.1399-0039.2010.01466.x

• Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0609174104

• A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1885

• Mother's little helpers: mechanisms of maternal-fetal tolerance

  Nature Immunology · 2006 · https://doi.org/10.1038/ni1317

• Nomenclature for factors of the HLA system, 2004

  International Journal of Immunogenetics · 2005 · https://doi.org/10.1111/j.1744-313x.2005.00509.x

• Nomenclature for factors of the HLA system, 2004

  Tissue Antigens · 2005 · https://doi.org/10.1111/j.1399-0039.2005.00379.x

• Nomenclature for Factors of the HLA System, 2004

  Human Immunology · 2005 · https://doi.org/10.1016/j.humimm.2005.02.002

• Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success

  The Journal of Experimental Medicine · 2004 · https://doi.org/10.1084/jem.20041214

• Gene map of the extended human MHC

  Nature Reviews Genetics · 2004 · https://doi.org/10.1038/nrg1489

• Comparative genomics of major histocompatibility complexes

  Immunogenetics · 2004 · https://doi.org/10.1007/s00251-004-0717-7

• Genetic Control of MHC Class II Expression

  Cell · 2002 · https://doi.org/10.1016/s0092-8674(02)00696-7

• Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS

  Nature Genetics · 2002 · https://doi.org/10.1038/ng934

• Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro

  Journal of Leukocyte Biology · 2002 · https://doi.org/10.1189/jlb.71.3.445

• Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei

  Journal of Cell Science · 2000 · https://doi.org/10.1242/jcs.113.9.1565

• Plasticity in the organization and sequences of human KIR/ILT gene families

  Proceedings of the National Academy of Sciences · 2000 · https://doi.org/10.1073/pnas.080588597

• A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

  Science · 1997 · https://doi.org/10.1126/science.277.5330.1306

• Map of the human MHC

  Immunology Today · 1993 · https://doi.org/10.1016/0167-5699(93)90234-c

• Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

  Nature · 1992 · https://doi.org/10.1038/355641a0

• Folate-binding protein is a marker for ovarian cancer.

  PubMed · 1991

• A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC

  Nature · 1991 · https://doi.org/10.1038/353357a0

• A novel gysteine-rich sequence motif

  Cell · 1991 · https://doi.org/10.1016/0092-8674(91)90229-r

• Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

  Nature · 1990 · https://doi.org/10.1038/348741a0

Current projects

No projects listed.