Manjeet K. Bolla

Research interests

Publications

• Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

  JAMA Oncology · 2022 · https://doi.org/10.1001/jamaoncol.2021.6744

• Genetic insights into biological mechanisms governing human ovarian ageing

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03779-7

• Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0537-1

• Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-020-0609-2

• Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

  The American Journal of Human Genetics · 2018 · https://doi.org/10.1016/j.ajhg.2018.11.002

• Identification of nine new susceptibility loci for endometrial cancer

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-05427-7

• A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0132-x

• Association analysis identifies 65 new breast cancer risk loci

  Nature · 2017 · https://doi.org/10.1038/nature24284

• Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3785

• Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3841

• RAD51B in Familial Breast Cancer

  PLoS ONE · 2016 · https://doi.org/10.1371/journal.pone.0153788

• Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

  PLoS Medicine · 2016 · https://doi.org/10.1371/journal.pmed.1002105

• PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

  Journal of Medical Genetics · 2016 · https://doi.org/10.1136/jmedgenet-2016-103839

• Age- and Tumor Subtype–Specific Breast Cancer Risk Estimates for CH EK 2 *1100delC Carriers

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2016.66.5844

• Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

  JNCI Journal of the National Cancer Institute · 2015 · https://doi.org/10.1093/jnci/djv036

• Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3412

• Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

  Nature Genetics · 2015 · 10.1038/ng.3242

• Identification of Novel Genetic Markers of Breast Cancer Survival

  JNCI Journal of the National Cancer Institute · 2015 · https://doi.org/10.1093/jnci/djv081

• MicroRNA Related Polymorphisms and Breast Cancer Risk

  PLoS ONE · 2014 · https://doi.org/10.1371/journal.pone.0109973

• Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

  Nature · 2014 · 10.1038/nature13545

• Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

  The American Journal of Human Genetics · 2013 · https://doi.org/10.1016/j.ajhg.2013.01.002

• Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2566

• Large-scale genotyping identifies 41 new loci associated with breast cancer risk

  Nature Genetics · 2013 · 10.1038/ng.2563

• Genome-wide association studies identify four ER negative–specific breast cancer risk loci

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2561

• CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death, Breast Cancer–Specific Death, and Increased Risk of a Second Breast Cancer

  Journal of Clinical Oncology · 2012 · https://doi.org/10.1200/jco.2012.42.7336

• Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study

  The Lancet · 2001 · https://doi.org/10.1016/s0140-6736(01)05330-2

Current projects

No projects listed.