James D. Brenton
Researcher Next ID · RN-027794
Researcher · Medicine
Cambridge, South Korea
- Works count
- 698
- Citation count
- 39,900
- H-index
- 79
- i10-index
- 217
Research interests
Publications
European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer
Annals of Oncology · 2021 · https://doi.org/10.1016/j.annonc.2021.11.013
European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer
Annals of Oncology · 2021 · https://doi.org/10.1016/j.annonc.2021.11.013
Shared heritability and functional enrichment across six solid cancers
Nature Communications · 2019 · https://doi.org/10.1038/s41467-018-08054-4
Enhanced detection of circulating tumor DNA by fragment size analysis
Science Translational Medicine · 2018 · https://doi.org/10.1126/scitranslmed.aat4921
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Nature Genetics · 2017 · https://doi.org/10.1038/ng.3826
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
Nature Communications · 2017 · 10.1038/ncomms14432
Dose-Response Association of CD8 + Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer
JAMA Oncology · 2017 · https://doi.org/10.1001/jamaoncol.2017.3290
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nature reviews. Cancer · 2017 · https://doi.org/10.1038/nrc.2017.7
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
Nature reviews. Cancer · 2015 · https://doi.org/10.1038/nrc4019
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
Nature Genetics · 2013 · https://doi.org/10.1038/ng.2564
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
The Lancet Oncology · 2013 · https://doi.org/10.1016/s1470-2045(13)70253-5
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
Nature · 2013 · https://doi.org/10.1038/nature12065
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
Nature · 2012 · https://doi.org/10.1038/nature10983
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
Science Translational Medicine · 2012 · 10.1126/scitranslmed.3003726
Rethinking ovarian cancer: recommendations for improving outcomes
Nature reviews. Cancer · 2011 · 10.1038/nrc3144
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
The Journal of Pathology · 2010 · 10.1002/path.2696
Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary
New England Journal of Medicine · 2009 · 10.1056/nejmoa0902542
Chromosomal instability determines taxane response
Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0811835106
The Extracellular Matrix Protein TGFBI Induces Microtubule Stabilization and Sensitizes Ovarian Cancers to Paclitaxel
Cancer Cell · 2007 · https://doi.org/10.1016/j.ccr.2007.11.014
Differential expression of selected histone modifier genes in human solid cancers
BMC Genomics · 2006 · https://doi.org/10.1186/1471-2164-7-90
Molecular Classification and Molecular Forecasting of Breast Cancer: Ready for Clinical Application?
Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.03.3845
Current projects
No projects listed.