Canhua Huang

Research interests

Publications

• Redox regulation: mechanisms, biology and therapeutic targets in diseases

  Signal Transduction and Targeted Therapy · 2025 · https://doi.org/10.1038/s41392-024-02095-6

• Macrophage plasticity: signaling pathways, tissue repair, and regeneration

  MedComm · 2024 · https://doi.org/10.1002/mco2.658

• Neoantigens: promising targets for cancer therapy

  Signal Transduction and Targeted Therapy · 2023 · https://doi.org/10.1038/s41392-022-01270-x

• Oral squamous cell carcinomas: state of the field and emerging directions

  International Journal of Oral Science · 2023 · https://doi.org/10.1038/s41368-023-00249-w

• Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment

  Bone Research · 2023 · https://doi.org/10.1038/s41413-023-00246-z

• Drug-induced oxidative stress in cancer treatments: Angel or devil?

  Redox Biology · 2023 · https://doi.org/10.1016/j.redox.2023.102754

• Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management

  Journal of Hematology & Oncology · 2022 · https://doi.org/10.1186/s13045-022-01313-4

• Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

  Journal of Hematology & Oncology · 2022 · https://doi.org/10.1186/s13045-022-01320-5

• Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A

  Molecular Oncology · 2021 · https://doi.org/10.1002/1878-0261.13079

• From purines to purinergic signalling: molecular functions and human diseases

  Signal Transduction and Targeted Therapy · 2021 · https://doi.org/10.1038/s41392-021-00553-z

• Oxidative stress and diabetes: antioxidative strategies

  Frontiers of Medicine · 2020 · https://doi.org/10.1007/s11684-019-0729-1

• NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

  Signal Transduction and Targeted Therapy · 2020 · https://doi.org/10.1038/s41392-020-00311-7

• Emerging role of tumor cell plasticity in modifying therapeutic response

  Signal Transduction and Targeted Therapy · 2020 · https://doi.org/10.1038/s41392-020-00313-5

• Surmounting cancer drug resistance: New insights from the perspective of N6-methyladenosine RNA modification

  Drug Resistance Updates · 2020 · https://doi.org/10.1016/j.drup.2020.100720

• The role of long noncoding RNAs in hepatocellular carcinoma

  Molecular Cancer · 2020 · https://doi.org/10.1186/s12943-020-01188-4

• Overcoming cancer therapeutic bottleneck by drug repurposing

  Signal Transduction and Targeted Therapy · 2020 · https://doi.org/10.1038/s41392-020-00213-8

• Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress

  Redox Biology · 2018 · https://doi.org/10.1016/j.redox.2018.11.005

• Ketoconazole exacerbates mitophagy to induce apoptosis by downregulating cyclooxygenase-2 in hepatocellular carcinoma

  Journal of Hepatology · 2018 · https://doi.org/10.1016/j.jhep.2018.09.022

• Redox regulation in tumor cell epithelial–mesenchymal transition: molecular basis and therapeutic strategy

  Signal Transduction and Targeted Therapy · 2017 · https://doi.org/10.1038/sigtrans.2017.36

• Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer

  Cancer Research · 2016 · https://doi.org/10.1158/0008-5472.can-15-2887

• Redox Regulation of Inflammation: Old Elements, a New Story

  Medicinal Research Reviews · 2014 · https://doi.org/10.1002/med.21330

• Redox homeostasis: the linchpin in stem cell self-renewal and differentiation

  Cell Death and Disease · 2013 · https://doi.org/10.1038/cddis.2013.50

• Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling

  Autophagy · 2011 · https://doi.org/10.4161/auto.7.9.15863

• RUNX3, A Novel Tumor Suppressor, Is Frequently Inactivated in Gastric Cancer by Protein Mislocalization

  Cancer Research · 2005 · https://doi.org/10.1158/0008-5472.can-05-0743

• Antiviral properties of hemocyanin isolated from shrimp Penaeus monodon

  Antiviral Research · 2003 · https://doi.org/10.1016/j.antiviral.2003.08.019

Current projects

No projects listed.