Carlos Martı́n

Research interests

Publications

• Safety of human immunisation with a live-attenuated Mycobacterium tuberculosis vaccine: a randomised, double-blind, controlled phase I trial

  The Lancet Respiratory Medicine · 2015 · https://doi.org/10.1016/s2213-2600(15)00435-x

• Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1406693111

• Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials

  Vaccine · 2013 · https://doi.org/10.1016/j.vaccine.2013.07.051

• High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

  PLoS Pathogens · 2010 · https://doi.org/10.1371/journal.ppat.1001100

• MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

  PLoS ONE · 2009 · https://doi.org/10.1371/journal.pone.0005264

• PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence

  PLoS ONE · 2008 · https://doi.org/10.1371/journal.pone.0003496

• Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP

  PLoS Pathogens · 2008 · https://doi.org/10.1371/journal.ppat.0040033

• Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology

  BMC Microbiology · 2006 · https://doi.org/10.1186/1471-2180-6-23

• The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs

  Vaccine · 2006 · https://doi.org/10.1016/j.vaccine.2006.03.017

• Characterisation of guinea pig precision-cut lung slices: comparison with human tissues

  European Respiratory Journal · 2006 · https://doi.org/10.1183/09031936.06.00004206

• The Virulence-associated Two-component PhoP-PhoR System Controls the Biosynthesis of Polyketide-derived Lipids in Mycobacterium tuberculosis

  Journal of Biological Chemistry · 2005 · https://doi.org/10.1074/jbc.c500388200

• Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

  Tuberculosis · 2005 · https://doi.org/10.1016/j.tube.2004.09.009

• IS 6110 Mediates Increased Transcription of the phoP Virulence Gene in a Multidrug-Resistant Clinical Isolate Responsible for Tuberculosis Outbreaks

  Journal of Clinical Microbiology · 2004 · https://doi.org/10.1128/jcm.42.1.212-219.2004

• Mutations in Putative Mutator Genes ofMycobacterium tuberculosisStrains of the W-Beijing Family

  Emerging infectious diseases · 2003 · https://doi.org/10.3201/eid0907.020803

• Exogenous Reinfection with Tuberculosis on a European Island with a Moderate Incidence of Disease

  American Journal of Respiratory and Critical Care Medicine · 2001 · https://doi.org/10.1164/ajrccm.163.3.2003070

• An essential role for phoP in Mycobacterium tuberculosis virulence

  Molecular Microbiology · 2001 · https://doi.org/10.1046/j.1365-2958.2001.02500.x

• High Rate of Tuberculosis Reinfection during a Nosocomial Outbreak of Multidrug-Resistant Tuberculosis Caused by Mycobacterium bovis Strain B

  Clinical Infectious Diseases · 2001 · https://doi.org/10.1086/317547

• Epidemiological Evidence of the Spread of a Mycobacterium tuberculosis Strain of the Beijing Genotype on Gran Canaria Island

  American Journal of Respiratory and Critical Care Medicine · 2001 · https://doi.org/10.1164/ajrccm.164.7.2101031

• Comparison of Methods Based on Different Molecular Epidemiological Markers for Typing of Mycobacterium tuberculosis Complex Strains: Interlaboratory Study of Discriminatory Power and Reproducibility

  Journal of Clinical Microbiology · 1999 · https://doi.org/10.1128/jcm.37.8.2607-2618.1999

• Molecular Cloning and Characterization of Tap, a Putative Multidrug Efflux Pump Present inMycobacterium fortuitumandMycobacterium tuberculosis

  Journal of Bacteriology · 1998 · https://doi.org/10.1128/jb.180.22.5836-5843.1998

• Videomicroscopy of methacholine-induced contraction of individual airways in precision-cut lung slices

  European Respiratory Journal · 1996 · https://doi.org/10.1183/09031936.96.09122479

• Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology

  Journal of Clinical Microbiology · 1993 · https://doi.org/10.1128/jcm.31.2.406-409.1993

• Transposition of an antibiotic resistance element in mycobacteria

  Nature · 1990 · https://doi.org/10.1038/345739a0

Current projects

No projects listed.