R. Douglas Shytle

Research interests

Publications

• Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration

  GeroScience · 2017 · https://doi.org/10.1007/s11357-017-9958-x

• Cocrystals of Quercetin with Improved Solubility and Oral Bioavailability

  Molecular Pharmaceutics · 2011 · https://doi.org/10.1021/mp200209j

• Green Tea Epigallocatechin-3-Gallate (EGCG) and Other Flavonoids Reduce Alzheimer's Amyloid-Induced Mitochondrial Dysfunction

  Journal of Alzheimer s Disease · 2011 · https://doi.org/10.3233/jad-2011-101629

• Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

  International Journal of Pharmaceutics · 2010 · https://doi.org/10.1016/j.ijpharm.2010.01.012

• Reliability and Validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

  The Journal of Clinical Psychiatry · 2010 · https://doi.org/10.4088/jcp.09m05305whi

• Flavonoid‐mediated presenilin‐1 phosphorylation reduces Alzheimer's disease β‐amyloid production

  Journal of Cellular and Molecular Medicine · 2008 · https://doi.org/10.1111/j.1582-4934.2008.00344.x

• Nicotinic Antagonist Augmentation of Selective Serotonin Reuptake Inhibitor-Refractory Major Depressive Disorder

  Journal of Clinical Psychopharmacology · 2008 · https://doi.org/10.1097/jcp.0b013e318172b49e

• Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

  Journal of Neuroinflammation · 2008 · https://doi.org/10.1186/1742-2094-5-41

• Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

  Brain Research · 2008 · https://doi.org/10.1016/j.brainres.2008.02.107

• Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

  Journal of Neuroinflammation · 2005 · https://doi.org/10.1186/1742-2094-2-29

• Cholinergic modulation of microglial activation by α7 nicotinic receptors

  Journal of Neurochemistry · 2004 · https://doi.org/10.1046/j.1471-4159.2004.02347.x

• Nicotine's oxidative and antioxidant properties in CNS

  Life Sciences · 2002 · https://doi.org/10.1016/s0024-3205(02)02135-5

• Nicotinic acetylcholine receptors as targets for antidepressants

  Molecular Psychiatry · 2002 · https://doi.org/10.1038/sj.mp.4001035

• Analysis of Mecamylamine Stereoisomers on Human Nicotinic Receptor Subtypes

  Journal of Pharmacology and Experimental Therapeutics · 2001 · https://doi.org/10.1016/s0022-3565(24)29581-1

Current projects

No projects listed.