John F. Cryan

Research interests

Publications

• The Microbiota-Gut-Brain Axis: From Motility to Mood

  Gastroenterology · 2021 · 10.1053/j.gastro.2020.10.066

• Diet and depression: exploring the biological mechanisms of action

  Molecular Psychiatry · 2020 · https://doi.org/10.1038/s41380-020-00925-x

• The Microbiota-Gut-Brain Axis

  Physiological Reviews · 2019 · https://doi.org/10.1152/physrev.00018.2018

• The gut microbiome in neurological disorders

  The Lancet Neurology · 2019 · 10.1016/s1474-4422(19)30356-4

• Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations

  The Journal of Physiology · 2018 · https://doi.org/10.1113/jp276431

• The Microbiome-Gut-Brain Axis in Health and Disease

  Gastroenterology Clinics of North America · 2017 · 10.1016/j.gtc.2016.09.007

• Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice

  Biological Psychiatry · 2017 · https://doi.org/10.1016/j.biopsych.2016.12.031

• Stress & the gut-brain axis: Regulation by the microbiome

  Neurobiology of Stress · 2017 · 10.1016/j.ynstr.2017.03.001

• Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals

  Trends in Neurosciences · 2016 · 10.1016/j.tins.2016.09.002

• The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?

  Neurochemistry International · 2016 · 10.1016/j.neuint.2016.06.011

• Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior

  The International Journal of Neuropsychopharmacology · 2016 · 10.1093/ijnp/pyw020

• Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

  Journal of Psychiatric Research · 2016 · https://doi.org/10.1016/j.jpsychires.2016.07.019

• Regulation of prefrontal cortex myelination by the microbiota

  Translational Psychiatry · 2016 · 10.1038/tp.2016.42

• Gut microbiota, obesity and diabetes

  Postgraduate Medical Journal · 2016 · 10.1136/postgradmedj-2015-133285

• Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

  The Journal of Physiology · 2016 · 10.1113/jp273106

• Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

  Brain Behavior and Immunity · 2015 · 10.1016/j.bbi.2015.04.004

• Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

  Frontiers in Cellular Neuroscience · 2015 · 10.3389/fncel.2015.00392

• Gut Microbes and the Brain: Paradigm Shift in Neuroscience

  Journal of Neuroscience · 2014 · 10.1523/jneurosci.3299-14.2014

• Microbiota and neurodevelopmental windows: implications for brain disorders

  Trends in Molecular Medicine · 2014 · 10.1016/j.molmed.2014.05.002

• Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

  Behavioural Brain Research · 2014 · https://doi.org/10.1016/j.bbr.2014.07.027

• Minireview: Gut Microbiota: The Neglected Endocrine Organ

  Molecular Endocrinology · 2014 · 10.1210/me.2014-1108

• Microbiota is essential for social development in the mouse

  Molecular Psychiatry · 2013 · 10.1038/mp.2013.65

• Psychobiotics: A Novel Class of Psychotropic

  Biological Psychiatry · 2013 · 10.1016/j.biopsych.2013.05.001

• Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test

  Neuroscience & Biobehavioral Reviews · 2013 · 10.1016/j.neubiorev.2013.11.005

• Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

  Nature reviews. Neuroscience · 2012 · https://doi.org/10.1038/nrn3346

• The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

  Molecular Psychiatry · 2012 · https://doi.org/10.1038/mp.2012.77

• Brain?Gut?Microbe Communication in Health and Disease

  Frontiers in Physiology · 2011 · 10.3389/fphys.2011.00094

• The microbiome-gut-brain axis: from bowel to behavior

  Neurogastroenterology & Motility · 2011 · 10.1111/j.1365-2982.2010.01664.x

• Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1102999108

• Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

  Neuroscience · 2010 · 10.1016/j.neuroscience.2010.08.005

• Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses

  Biological Psychiatry · 2008 · 10.1016/j.biopsych.2008.06.026

• The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice

  Neuroscience & Biobehavioral Reviews · 2005 · 10.1016/j.neubiorev.2005.03.009

• Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test

  Neuroscience & Biobehavioral Reviews · 2005 · 10.1016/j.neubiorev.2005.03.008

• The ascent of mouse: advances in modelling human depression and anxiety

  Nature Reviews Drug Discovery · 2005 · 10.1038/nrd1825

• Assessing antidepressant activity in rodents: recent developments and future needs

  Trends in Pharmacological Sciences · 2002 · 10.1016/s0165-6147(02)02017-5

Current projects

No projects listed.