Gustavo Turecki

Research interests

Publications

• Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

  Nature Neuroscience · 2020 · 10.1038/s41593-020-0621-y

• Suicide and suicide risk

  Nature Reviews Disease Primers · 2019 · https://doi.org/10.1038/s41572-019-0121-0

• The emerging role of exosomes in mental disorders

  Translational Psychiatry · 2019 · 10.1038/s41398-019-0459-9

• Sex-specific transcriptional signatures in human depression

  Nature Medicine · 2017 · 10.1038/nm.4386

• Social stress induces neurovascular pathology promoting depression

  Nature Neuroscience · 2017 · https://doi.org/10.1038/s41593-017-0010-3

• Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

  The Lancet · 2016 · 10.1016/s0140-6736(16)00143-4

• Suicide and suicidal behaviour

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(15)00234-2

• Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

  Nature Neuroscience · 2015 · 10.1038/nn.4182

• Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

  Journal of Neuroscience · 2015 · 10.1523/jneurosci.1392-15.2015

• Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

  Brain Behavior and Immunity · 2014 · 10.1016/j.bbi.2014.05.007

• Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review

  Biological Psychiatry · 2014 · https://doi.org/10.1016/j.biopsych.2014.11.022

• Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

  PLoS ONE · 2013 · 10.1371/journal.pone.0065636

• Genome-wide Epigenetic Regulation by Early-Life Trauma

  Archives of General Psychiatry · 2012 · 10.1001/archgenpsychiatry.2011.2287

• Conserved role of intragenic DNA methylation in regulating alternative promoters

  Nature · 2010 · https://doi.org/10.1038/nature09165

• Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

  PLoS ONE · 2009 · 10.1371/journal.pone.0006585

• Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

  Nature Neuroscience · 2009 · https://doi.org/10.1038/nn.2270

• Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain

  PLoS ONE · 2008 · 10.1371/journal.pone.0002085

• Definition, Assessment, and Staging of Treatment—Resistant Refractory Major Depression: A Review of Current Concepts and Methods

  The Canadian Journal of Psychiatry · 2007 · 10.1177/070674370705200108

• Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

  Nature Genetics · 2007 · https://doi.org/10.1038/ng2099

• Personality traits as correlates of suicidal ideation, suicide attempts, and suicide completions: a systematic review

  Acta Psychiatrica Scandinavica · 2006 · 10.1111/j.1600-0447.2005.00702.x

• Risk Factors for Suicide Completion in Major Depression: A Case-Control Study of Impulsive and Aggressive Behaviors in Men

  American Journal of Psychiatry · 2005 · 10.1176/appi.ajp.162.11.2116

• Psychiatric diagnoses in 3275 suicides: a meta-analysis

  BMC Psychiatry · 2004 · 10.1186/1471-244x-4-37

• A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior

  Molecular Psychiatry · 2003 · 10.1038/sj.mp.4001336

• Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide

  Journal of Neuroscience · 2003 · 10.1523/jneurosci.23-25-08788.2003

• Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder

  The American Journal of Human Genetics · 2003 · 10.1086/376547

Current projects

No projects listed.