Muredach P. Reilly

Research interests

Publications

• The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

  Nature · 2021 · 10.1038/s41586-021-03341-5

• Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis

  Nature Communications · 2020 · 10.1038/s41467-020-15851-3

• Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human

  Circulation · 2020 · 10.1161/circulationaha.120.048378

• Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

  Nature · 2014 · https://doi.org/10.1038/nature13917

• Identification of seven loci affecting mean telomere length and their association with disease

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2528

• Association between Albuminuria, Kidney Function, and Inflammatory Biomarker Profile in CKD in CRIC

  Clinical Journal of the American Society of Nephrology · 2012 · 10.2215/cjn.03500412

• Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

  The Lancet · 2011 · 10.1016/s0140-6736(10)61996-4

• Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.784

• Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

  Diabetes · 2010 · 10.2337/db10-0502

• Meta-analysis and imputation refines the association of 15q25 with smoking quantity

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.572

• Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.327

• Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta‐analysis

  Journal of Thrombosis and Haemostasis · 2009 · 10.1111/j.1538-7836.2009.03584.x

• Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

  Nature Genetics · 2009 · 10.1038/ng.323

• The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

  Nature Genetics · 2008 · 10.1038/ng.72

• Leptin Resistance

  Journal of the American College of Cardiology · 2008 · 10.1016/j.jacc.2008.05.060

• Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

  Nature Genetics · 2007 · 10.1038/ng2062

• Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

  Nature Genetics · 2007 · 10.1038/ng1960

• A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction

  Science · 2007 · 10.1126/science.1142842

• A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

  Nature Genetics · 2007 · 10.1038/ng2043

• Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

  Nature Genetics · 2006 · 10.1038/ng1732

• Resistin Is an Inflammatory Marker of Atherosclerosis in Humans

  Circulation · 2005 · 10.1161/01.cir.0000155620.10387.43

• An Inflammatory Cascade Leading to Hyperresistinemia in Humans

  PLoS Medicine · 2004 · 10.1371/journal.pmed.0010045

• Overexpression of Apolipoprotein A-I Promotes Reverse Transport of Cholesterol From Macrophages to Feces In Vivo

  Circulation · 2003 · 10.1161/01.cir.0000086981.09834.e0

• The Metabolic Syndrome

  Circulation · 2003 · 10.1161/01.cir.0000088846.10655.e0

• Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin

  New England Journal of Medicine · 2001 · 10.1056/nejmoa003199

Current projects

No projects listed.