Guy Thwaites

Research interests

Publications

• The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

  The Lancet Microbe · 2022 · 10.1016/s2666-5247(21)00301-3

• Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): preliminary results of a randomised, controlled, open-label, platform trial

  medRxiv · 2021 · 10.1101/2021.02.11.21249258

• Critical analysis of antibacterial agents in clinical development

  Nature Reviews Microbiology · 2020 · 10.1038/s41579-020-0340-0

• Oral versus Intravenous Antibiotics for Bone and Joint Infection

  New England Journal of Medicine · 2019 · https://doi.org/10.1056/nejmoa1710926

• Tuberculous meningitis

  Nature Reviews Neurology · 2017 · 10.1038/nrneurol.2017.120

• Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

  The Lancet Infectious Diseases · 2017 · https://doi.org/10.1016/s1473-3099(17)30753-3

• Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis

  New England Journal of Medicine · 2016 · 10.1056/nejmoa1507062

• Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis

  New England Journal of Medicine · 2016 · 10.1056/nejmoa1509024

• Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3281

• Tuberculous meningitis: more questions, still too few answers

  The Lancet Neurology · 2013 · 10.1016/s1474-4422(13)70168-6

• Staphylococcus aureus bloodstream infection: A pooled analysis of five prospective, observational studies

  Journal of Infection · 2013 · 10.1016/j.jinf.2013.10.015

• Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2744

• Dilemmas in the diagnosis of acute community-acquired bacterial meningitis

  The Lancet · 2012 · 10.1016/s0140-6736(12)61185-4

• Advances in treatment of bacterial meningitis

  The Lancet · 2012 · 10.1016/s0140-6736(12)61186-6

• Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

  Cell · 2012 · 10.1016/j.cell.2011.12.023

• Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?

  Nature Reviews Microbiology · 2011 · 10.1038/nrmicro2508

• Tuberculous meningitis: a uniform case definition for use in clinical research

  The Lancet Infectious Diseases · 2010 · https://doi.org/10.1016/s1473-3099(10)70138-9

• British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children

  Journal of Infection · 2009 · 10.1016/j.jinf.2009.06.011

• The Influence of Host and Bacterial Genotype on the Development of Disseminated Disease with Mycobacterium tuberculosis

  PLoS Pathogens · 2008 · 10.1371/journal.ppat.1000034

• Tuberculous meningitis: many questions, too few answers

  The Lancet Neurology · 2005 · 10.1016/s1474-4422(05)01013-6

• Tuberculous meningitis: many questions, too few answers

  The Lancet Neurology · 2005 · 10.1016/s1474-4422(05)70019-3

• Dexamethasone for the Treatment of Tuberculous Meningitis in Adolescents and Adults

  New England Journal of Medicine · 2004 · 10.1056/nejmoa040573

• Improving the Bacteriological Diagnosis of Tuberculous Meningitis

  Journal of Clinical Microbiology · 2004 · 10.1128/jcm.42.1.378-379.2004

• Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features

  The Lancet · 2002 · 10.1016/s0140-6736(02)11318-3

• Neurological aspects of tropical disease: Tuberculous meningitis

  Journal of Neurology Neurosurgery & Psychiatry · 2000 · 10.1136/jnnp.68.3.289

Current projects

No projects listed.