David B. Jaffe

Research interests

Publications

• Genomic architecture and introgression shape a butterfly radiation

  Science · 2019 · 10.1126/science.aaw2090

• Direct determination of diploid genome sequences

  Genome Research · 2017 · 10.1101/gr.214874.116

• The genomic substrate for adaptive radiation in African cichlid fish

  Nature · 2014 · https://doi.org/10.1038/nature13726

• Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

  Nature Biotechnology · 2013 · 10.1038/nbt.2514

• Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

  GigaScience · 2013 · https://doi.org/10.1186/2047-217x-2-10

• Characterizing and measuring bias in sequence data

  Genome biology · 2013 · 10.1186/gb-2013-14-5-r51

• The African coelacanth genome provides insights into tetrapod evolution

  Nature · 2013 · 10.1038/nature12027

• Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

  Nature Biotechnology · 2013 · 10.1038/nbt.2514

• Demographic history and rare allele sharing among human populations

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1019276108

• Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries

  Genome biology · 2011 · 10.1186/gb-2011-12-2-r18

• A high-resolution map of human evolutionary constraint using 29 mammals

  Nature · 2011 · https://doi.org/10.1038/nature10530

• Assemblathon 1: A competitive assessment of de novo short read assembly methods

  Genome Research · 2011 · 10.1101/gr.126599.111

• High-quality draft assemblies of mammalian genomes from massively parallel sequence data

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1017351108

• A map of human genome variation from population-scale sequencing

  Nature · 2010 · https://doi.org/10.1038/nature09534

• Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

  Nature Biotechnology · 2009 · 10.1038/nbt.1523

• High-resolution mapping of copy-number alterations with massively parallel sequencing

  Nature Methods · 2008 · 10.1038/nmeth.1276

• ALLPATHS: De novo assembly of whole-genome shotgun microreads

  Genome Research · 2008 · 10.1101/gr.7337908

• Genome-scale DNA methylation maps of pluripotent and differentiated cells

  Nature · 2008 · 10.1038/nature07107

• Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

  Nature · 2007 · 10.1038/nature06008

• Evolution of genes and genomes on the Drosophila phylogeny

  Nature · 2007 · 10.1038/nature06341

• Genome Sequence of Aedes aegypti , a Major Arbovirus Vector

  Science · 2007 · 10.1126/science.1138878

• Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis

  Nature · 2006 · 10.1038/nature05248

• Genome sequence, comparative analysis and haplotype structure of the domestic dog

  Nature · 2005 · 10.1038/nature04338

• Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

  Nature · 2004 · 10.1038/nature03025

• The genome sequence of the filamentous fungus Neurospora crassa

  Nature · 2003 · 10.1038/nature01554

• Initial sequencing and comparative analysis of the mouse genome

  Nature · 2002 · 10.1038/nature01262

Current projects

No projects listed.