Peter ten Dijke

Research interests

Publications

• Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

  Cell · 2022 · https://doi.org/10.1016/j.cell.2021.12.018

• TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis

  International Journal of Molecular Sciences · 2019 · https://doi.org/10.3390/ijms20112767

• Targeting TGF-β Signaling in Cancer

  Trends in cancer · 2017 · https://doi.org/10.1016/j.trecan.2016.11.008

• TGF ‐β signalling and liver disease

  FEBS Journal · 2016 · https://doi.org/10.1111/febs.13665

• Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

  Nature Protocols · 2014 · https://doi.org/10.1038/nprot.2014.102

• TGF-β in progression of liver disease

  Cell and Tissue Research · 2011 · https://doi.org/10.1007/s00441-011-1246-y

• TGF-β signaling in vascular biology and dysfunction

  Cell Research · 2008 · https://doi.org/10.1038/cr.2008.326

• Extracellular control of TGFβ signalling in vascular development and disease

  Nature Reviews Molecular Cell Biology · 2007 · https://doi.org/10.1038/nrm2262

• Transforming Growth Factor-β1 to the Bone

  Endocrine Reviews · 2005 · https://doi.org/10.1210/er.2004-0001

• New insights into TGF-β–Smad signalling

  Trends in Biochemical Sciences · 2004 · https://doi.org/10.1016/j.tibs.2004.03.008

• Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction

  The EMBO Journal · 2004 · https://doi.org/10.1038/sj.emboj.7600386

• Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist

  The Journal of Experimental Medicine · 2004 · https://doi.org/10.1084/jem.20031454

• Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

  Molecular Cell · 2003 · https://doi.org/10.1016/s1097-2765(03)00386-1

• Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

  Molecular Cell · 2003 · https://doi.org/10.1016/s1097-2765(03)00386-1

• Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

  The EMBO Journal · 2002 · https://doi.org/10.1093/emboj/21.7.1743

• Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m111023200

• Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice

  The EMBO Journal · 2001 · https://doi.org/10.1093/emboj/20.7.1663

• Apoptosis in podocytes induced by TGF-β and Smad7

  Journal of Clinical Investigation · 2001 · https://doi.org/10.1172/jci200112367

• Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

  Proceedings of the National Academy of Sciences · 2000 · https://doi.org/10.1073/pnas.97.6.2626

• Specificity, diversity, and regulation in TGF‐β superfamily signaling

  The FASEB Journal · 1999 · https://doi.org/10.1096/fasebj.13.15.2105

• Specificity, diversity, and regulation in TGF-beta superfamily signaling.

  PubMed · 1999

• Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.33.21145

• Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

  The EMBO Journal · 1998 · https://doi.org/10.1093/emboj/17.11.3091

• Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

  Science · 1997 · https://doi.org/10.1126/science.275.5296.90

• TGF-β signalling from cell membrane to nucleus through SMAD proteins

  Nature · 1997 · https://doi.org/10.1038/37284

• Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

  Nature · 1997 · https://doi.org/10.1038/39369

• TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4

  The EMBO Journal · 1997 · https://doi.org/10.1093/emboj/16.17.5353

• Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

  Journal of Biological Chemistry · 1994 · https://doi.org/10.1016/s0021-9258(17)32506-1

Current projects

No projects listed.