T. Huizinga

Research interests

Publications

• Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01213-w

• EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

  Annals of the Rheumatic Diseases · 2020 · https://doi.org/10.1136/annrheumdis-2019-216655

• EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

  Annals of the Rheumatic Diseases · 2017 · https://doi.org/10.1136/annrheumdis-2016-210715

• Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis

  PLoS Genetics · 2013 · https://doi.org/10.1371/journal.pgen.1003394

• Genetics of rheumatoid arthritis contributes to biology and drug discovery

  Nature · 2013 · https://doi.org/10.1038/nature12873

• Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

  Osteoarthritis and Cartilage · 2012 · 10.1016/j.joca.2012.08.027

• High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2462

• EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

  Annals of the Rheumatic Diseases · 2012 · https://doi.org/10.1136/annrheumdis-2011-200990

• Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

  Annals of the Rheumatic Diseases · 2012 · https://doi.org/10.1136/annrheumdis-2011-201282

• EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

  Annals of the Rheumatic Diseases · 2010 · https://doi.org/10.1136/ard.2009.126532

• Rheumatoid arthritis

  The Lancet · 2010 · https://doi.org/10.1016/s0140-6736(10)60826-4

• 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

  Annals of the Rheumatic Diseases · 2010 · https://doi.org/10.1136/ard.2010.138461

• 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

  Arthritis & Rheumatism · 2010 · https://doi.org/10.1002/art.27584

• Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

  Nature Genetics · 2010 · 10.1038/ng.582

• EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs

  Annals of the Rheumatic Diseases · 2010 · 10.1136/ard.2010.130476

• Association between weight or body mass index and hand osteoarthritis: a systematic review

  Annals of the Rheumatic Diseases · 2009 · https://doi.org/10.1136/ard.2008.106930

• Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis

  Annals of the Rheumatic Diseases · 2008 · https://doi.org/10.1136/ard.2008.092254

• A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent‐onset rheumatoid arthritis

  Arthritis & Rheumatism · 2007 · https://doi.org/10.1002/art.22640

• Translating Pharmacogenomics: Challenges on the Road to the Clinic

  PLoS Medicine · 2007 · https://doi.org/10.1371/journal.pmed.0040209

• EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics

  Annals of the Rheumatic Diseases · 2007 · 10.1136/ard.2007.070367

• Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis

  Lara D. Veeken · 2007 · https://doi.org/10.1093/rheumatology/kem279

• Transient expression of FOXP3 in human activated nonregulatory CD4 + T cells

  European Journal of Immunology · 2006 · 10.1002/eji.200636435

• Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single‐nucleotide polymorphisms in genes coding for folate pathway enzymes

  Arthritis & Rheumatism · 2006 · https://doi.org/10.1002/art.21726

• Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins

  Arthritis & Rheumatism · 2005 · 10.1002/art.21385

• Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: A prospective cohort study

  Arthritis & Rheumatism · 2004 · 10.1002/art.20044

• Cytokine gene polymorphism in human disease: on-line databases

  Genes and Immunity · 1999 · 10.1038/sj.gene.6363645

• Genetic influence on cytokine production and fatal meningococcal disease

  The Lancet · 1997 · 10.1016/s0140-6736(96)06413-6

Current projects

No projects listed.