Derek W. Gilroy

Research interests

Publications

• Immune boosting by B.1.1.529 ( Omicron) depends on previous SARS-CoV-2 exposure

  Science · 2022 · 10.1126/science.abq1841

• Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2

  Nature · 2021 · 10.1038/s41586-021-04186-8

• A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis

  New England Journal of Medicine · 2021 · 10.1056/nejmoa2022166

• Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

  Science · 2021 · 10.1126/science.abh1282

• Sestrins induce natural killer function in senescent-like CD8+ T cells

  Nature Immunology · 2020 · 10.1038/s41590-020-0643-3

• Chronic inflammation in the etiology of disease across the life span

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0675-0

• The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

  The Journal of Experimental Medicine · 2017 · https://doi.org/10.1084/jem.20170355

• A sestrin-dependent Erk–Jnk–p38 MAPK activation complex inhibits immunity during aging

  Nature Immunology · 2017 · 10.1038/ni.3665

• Resolution of inflammation: a new therapeutic frontier

  Nature Reviews Drug Discovery · 2016 · 10.1038/nrd.2016.39

• Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

  Immunity · 2014 · https://doi.org/10.1016/j.immuni.2014.02.009

• Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2

  Nature Medicine · 2014 · 10.1038/nm.3516

• Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

  Immunity · 2014 · https://doi.org/10.1016/j.immuni.2014.06.008

• The resolution of inflammation

  Nature reviews. Immunology · 2012 · 10.1038/nri3362

• Transcriptomic analyses of murine resolution-phase macrophages

  Blood · 2011 · 10.1182/blood-2011-04-345330

• Sex differences in resident immune cell phenotype underlie more efficient acute inflammatory responses in female mice

  Blood · 2011 · 10.1182/blood-2011-03-340281

• Old and new generation lipid mediators in acute inflammation and resolution

  Progress in Lipid Research · 2010 · 10.1016/j.plipres.2010.07.005

• Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans

  The Journal of Immunology · 2009 · 10.4049/jimmunol.0900477

• Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

  Blood · 2008 · 10.1182/blood-2007-12-129767

• Hematopoietic prostaglandin D 2 synthase controls the onset and resolution of acute inflammation through PGD 2 and 15-deoxyΔ 12–14 PGJ 2

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0707394104

• Resolution of in flammation: state of the art, definitions and terms

  The FASEB Journal · 2007 · https://doi.org/10.1096/fj.06-7227rev

• Chronic inflammation: a failure of resolution?

  International Journal of Experimental Pathology · 2006 · 10.1111/j.1365-2613.2006.00507.x

• Inflammatory Resolution: new opportunities for drug discovery

  Nature Reviews Drug Discovery · 2004 · 10.1038/nrd1383

• Anti-inflammatory lipid mediators and insights into the resolution of inflammation

  Nature reviews. Immunology · 2002 · 10.1038/nri915

• Possible new role for NF-κB in the resolution of inflammation

  Nature Medicine · 2001 · 10.1038/nm1201-1291

• Inducible cyclooxygenase may have anti-inflammatory properties

  Nature Medicine · 1999 · 10.1038/9550

Current projects

No projects listed.